E-ISSN 1658-7820
 
2024, Vol: 8, Issue: 5
8 / 5Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Review Article

Online Publishing Date:
18 / 12 / 2023

 


Efficacy and safety of ibuprofen in postoperative pain management among children; systematic review

Mohammed Hassan Almuntashiri, Hamed Abdullah Alshamrani, Abdulaziz Mohammad Alqurashi, Khaled Awadh Alharthy, Abdulmjeed Awadh Almotairi, Yasir Abdul Al Aziz Al Otibi.


Abstract
Postoperative pain management is a critical aspect of care in pediatric patients undergoing surgical procedures. Ibuprofen has been examined as a treatment for mild to moderate pain in the postoperative management of children. This systematic review aimed to evaluate the efficacy and safety of ibuprofen in managing postoperative pain among children. A literature review was conducted using PubMed from 2013 to 2023. Keywords "ibuprofen," "efficacy," "safety," and "postoperative" were used for the research process. All relevant articles evaluating the efficacy and safety of ibuprofen in managing postoperative pain among children (under 18 years old) were included. The search identified 42 papers through PubMed databases. Only five studies met the objective of the systematic review. The included studies were a pooled analysis study (n=534), a prospective, double-blind, randomized clinical trial (n=30), a retrospective study (n=1065), and a multicenter, randomized, double-blind, placebo-controlled trial (n=161). Moreover, the total number of patients was 1,850, aged 1 to 19 years. Ibuprofen (oral or intravenous) and acetaminophen were the interventions examined in the included studies. The findings from the included studies suggested that ibuprofen is an effective analgesic option for children undergoing various surgical procedures. The reviewed studies consistently reported a favorable safety profile for ibuprofen in pediatric patients, with minimal incidence of adverse events. Further research with more studies is needed to expand the understanding of optimal pain management strategies in pediatric surgery and explore the comparative effectiveness of different analgesic interventions.

Key words: Ibuprofen, safety, efficacy, postoperative, pediatric surgery


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Mohammed Hassan Almuntashiri
Articles by Hamed Abdullah Alshamrani
Articles by Abdulaziz Mohammad Alqurashi
Articles by Khaled Awadh Alharthy
Articles by Abdulmjeed Awadh Almotairi
Articles by Yasir Abdul Al Aziz Al Otibi
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Almuntashiri MH, Alshamrani HA, Alqurashi AM, Alharthy KA, Almotairi AA, . Efficacy and safety of ibuprofen in postoperative pain management among children; systematic review. IJMDC. 2024; 8(1): 349-353. doi:10.24911/IJMDC.51-1700033174

Web Style

Almuntashiri MH, Alshamrani HA, Alqurashi AM, Alharthy KA, Almotairi AA, . Efficacy and safety of ibuprofen in postoperative pain management among children; systematic review. https://www.ijmdc.com/?mno=177521 [Access: May 12, 2024]. doi:10.24911/IJMDC.51-1700033174

AMA (American Medical Association) Style

Almuntashiri MH, Alshamrani HA, Alqurashi AM, Alharthy KA, Almotairi AA, . Efficacy and safety of ibuprofen in postoperative pain management among children; systematic review. IJMDC. 2024; 8(1): 349-353. doi:10.24911/IJMDC.51-1700033174


Vancouver/ICMJE Style

Almuntashiri MH, Alshamrani HA, Alqurashi AM, Alharthy KA, Almotairi AA, . Efficacy and safety of ibuprofen in postoperative pain management among children; systematic review. IJMDC. (2024), [cited May 12, 2024]; 8(1): 349-353. doi:10.24911/IJMDC.51-1700033174


Harvard Style

Almuntashiri, M. H., Alshamrani, . H. A., Alqurashi, . A. M., Alharthy, . K. A., Almotairi, . A. A. & (2024) Efficacy and safety of ibuprofen in postoperative pain management among children; systematic review. IJMDC, 8 (1), 349-353. doi:10.24911/IJMDC.51-1700033174


Turabian Style

Almuntashiri, Mohammed Hassan, Hamed Abdullah Alshamrani, Abdulaziz Mohammad Alqurashi, Khaled Awadh Alharthy, Abdulmjeed Awadh Almotairi, and Yasir Abdul Al Aziz Al Otibi. 2024. Efficacy and safety of ibuprofen in postoperative pain management among children; systematic review. International Journal of Medicine in Developing Countries, 8 (1), 349-353. doi:10.24911/IJMDC.51-1700033174


Chicago Style

Almuntashiri, Mohammed Hassan, Hamed Abdullah Alshamrani, Abdulaziz Mohammad Alqurashi, Khaled Awadh Alharthy, Abdulmjeed Awadh Almotairi, and Yasir Abdul Al Aziz Al Otibi. "Efficacy and safety of ibuprofen in postoperative pain management among children; systematic review." International Journal of Medicine in Developing Countries 8 (2024), 349-353. doi:10.24911/IJMDC.51-1700033174


MLA (The Modern Language Association) Style

Almuntashiri, Mohammed Hassan, Hamed Abdullah Alshamrani, Abdulaziz Mohammad Alqurashi, Khaled Awadh Alharthy, Abdulmjeed Awadh Almotairi, and Yasir Abdul Al Aziz Al Otibi. "Efficacy and safety of ibuprofen in postoperative pain management among children; systematic review." International Journal of Medicine in Developing Countries 8.1 (2024), 349-353. Print. doi:10.24911/IJMDC.51-1700033174


APA (American Psychological Association) Style

Almuntashiri, M. H., Alshamrani, . H. A., Alqurashi, . A. M., Alharthy, . K. A., Almotairi, . A. A. & (2024) Efficacy and safety of ibuprofen in postoperative pain management among children; systematic review. International Journal of Medicine in Developing Countries, 8 (1), 349-353. doi:10.24911/IJMDC.51-1700033174




Most Viewed Articles
Most Accessed Articles

  • Marginal adaptation of fixed prosthodontics
    Shahad Mohammed Halawani, Sahar Amer Al-Harbi
    IJMDC. 2017; 1(2): 78-84
    » Abstract » doi: 10.24911/IJMDC.1.2.7

  • Parasites in central nervous system
    Amal Ahmed Mohamed, Asmaa Mohamed Mansour
    IJMDC. 2017; 1(2): 72-77
    » Abstract » doi: 10.24911/IJMDC.1.2.6

  • Non-diabetic retinopathy: a case report
    Hassan F. Alkwikbi, Nabil Mamon Abdelfattah, Haithem Mamon Abdelfattah
    IJMDC. 2017; 1(1): 33-37
    » Abstract » doi: 10.24911/IJMDC.1.1.6

  • Vitamin D deficiency among high school female students in Riyadh
    Sahar Mohsen Aldhafeeri, Fatemah Ibraheem Alrawaji, Abrar Mubarak Algharbi, Alanoud Abdullah Alhessan, Ayat Sami Qabaja, Ghaleah Abdulaziz Alnassar, Ghaliah Ofayn Alsulami, Mashael Belal Alrubaian, Norah Abdulaziz Alhatim, Salehah Salih Alotaibi, Zahra Ali Alkhamees
    IJMDC. 2017; 1(1): 18-23
    » Abstract » doi: 10.24911/IJMDC.1.1.4

  • Prognosis of chronic complications of diabetes mellitus (DM) after multiple events of diabetic ketoacidosis (DKA)
    Baraa Faiez Rajab, Anwar Essa Alamrim, Ali Essa Alamri
    IJMDC. 2019; 3(5): 474-479
    » Abstract » doi: 10.24911/IJMDC.51-1546551993

    •
    Most Downloaded
    Top Downloaded Articles

  • Anti-IL-17 markedly inhibited the in vitro granuloma induced by Schistosoma mansoni soluble egg antigen.
    Asmaa Ezz, Irene S. Gmail, Fatma Elzahraa H. Salem, Rabab Salama, Soad Nady
    IJMDC. 2018; 2(January 2018): 38-46
    » Abstract » doi: 10.24911/IJMDC.2.1.7

  • Vitamin D deficiency among high school female students in Riyadh
    Sahar Mohsen Aldhafeeri, Fatemah Ibraheem Alrawaji, Abrar Mubarak Algharbi, Alanoud Abdullah Alhessan, Ayat Sami Qabaja, Ghaleah Abdulaziz Alnassar, Ghaliah Ofayn Alsulami, Mashael Belal Alrubaian, Norah Abdulaziz Alhatim, Salehah Salih Alotaibi, Zahra Ali Alkhamees
    IJMDC. 2017; 1(1): 18-23
    » Abstract » doi: 10.24911/IJMDC.1.1.4

  • Antibiotic Resistance Crisis
    Nuha Saad Mobarki, Buthaina Abdullah Almerabi, Ahmad Hattan Hattan
    IJMDC. 2019; 3(6): 561-564
    » Abstract » doi: 10.24911/IJMDC.51-1549060699

  • The knowledge of mothers about children malnutrition and associated factors
    Anas Abdulrahman Aljohani, Mujahid Abdulrahman Aljohani
    IJMDC. 2020; 4(1): 7-11
    » Abstract » doi: 10.24911/IJMDC.51-1541620358

  • Knowledge and attitude of caregivers of cerebral palsy children in Riyadh city
    Abdulaziz Alruwaished, Baleegh Ali, Lubna Abdullah Alhowaimil , Abaraa adullah Alhowaimil, Najd Abdullah Alhowaimil, Aminah Alessa
    IJMDC. 2020; 4(1): 12-17
    » Abstract » doi: 10.24911/IJMDC.51-1547833051

    •
    Most Cited Articles
    Most Cited Articles

  • Antibiotic Resistance Crisis
    Nuha Saad Mobarki, Buthaina Abdullah Almerabi, Ahmad Hattan Hattan
    IJMDC. 2019; 3(6): 561-564
    » Abstract » doi: 10.24911/IJMDC.51-1549060699
    Cited : 34 times [Click to see citing articles]

  • Prevalence of depression, anxiety and stress among diabetes mellitus patients in Arar, Northern Saudi Arabia
    AMohammed Elamin Mukrim, Nujud Muteb D. Alshammari, Wurud Muteb D. Alshammari, Maali Subhi T. Alshammari, Yousef Nasif R. Alshammari, Abdulaziz Sael M. Alshammari, Maisa Hamad F. Alanazi, Abdulelah Abdulrhman F. Alzammam, Muharib Mana M. Alshammari, Slwa Khaled Abu Asyah, Aseel Jamal Alzuhayri, Mushref Saeid Alshammari
    IJMDC. 2019; 3(3): 229-233
    » Abstract » doi: 10.24911/IJMDC.51-1542576396
    Cited : 8 times [Click to see citing articles]

  • Knowledge, attitude, and practice of breast self-examination toward breast cancer among female students at King Saud University in Riyadh, Saudi Arabia
    Abdullah Nasser Alomair, Dania Ghazi Felemban, Mohannad Sami Felemban, Jameel Abdullah Awadain, Ammar Saud Altowairqi, Nawaf Fawzan Alfawzan, Fatimah Mohammed Almazayen, Abdulrahman Jalwi Korkoman, Nawaf Saad Alrusayyis
    IJMDC. 2020; 4(2): 429-434
    » Abstract » doi: 10.24911/IJMDC.51-1576668182
    Cited : 8 times [Click to see citing articles]

  • Population awareness about rheumatoid arthritis in Jazan region, Saudi Arabia
    Ahmad Ali Hazzazi, Mohssen Hassen Ageeli, Ahmed Ali Muyidi, Abdulaziz Mohammad Abulgasim, Abdullah Ahmad Yateemi, Nabil Alhakami
    IJMDC. 2020; 4(3): 668-675
    » Abstract » doi: 10.24911/IJMDC.51-1576010943
    Cited : 4 times [Click to see citing articles]

  • Prevalence and factors associated with depression among health care workers in National Guard Hospital in Riyadh, KSA
    Noor Mohammad AlFahhad
    IJMDC. 2018; 2(September 2018): 92-96
    » Abstract » doi: 10.24911/IJMDC.51-1526306040
    Cited : 4 times [Click to see citing articles]

    •

    About International Journal of Medicine in Developing Countries

    International Journal of Medicine in Developing Countries is a peer-reviewed, open access international medical journal. Journal Title Internat ... Read more.



    For best results, please use Internet Explorer or Google Chrome.

    Contact Information

    Publisher: Discover STM Publishing Ltd. 164 Moyville. Rathfarnham, Dublin, D16Y4E, Ireland

    Hours:  M-F: 7:30am - 4:30pm 

    Fax: +353 (0)1 633 5037 

    Emails:

    Journal Editorial Office:  contact@ijmdc.com

    All queries regarding the publishing or accepting of the manuscript should be directed to the Journal Editorial Office at Riyadh, Saudi Arabia. 

    Publishing and Hosting service is provided by Discover STM (Ireland):  contact@discoverpublish.com
    POLICIES & JOURNAL LINKS
    Author Login
    Reviewer Login
    About Publisher
    Advertising Policy
    Author's Rights and Obligations
    Conflict of Interest Policy
    Copyright Information
    Digital Archiving & Preservation Policies
    Editorial Policies
    Peer Review Policy
    Editorial & Peer Review Process
    License Information
    Open Access Policy
    Plagiarism Policy
    Privacy Policy
    Protection of Research Participants (Statement On Human And Animal Rights)
    Publication Ethics and Publication Malpractice Statement
    Corrections, Retractions & Expressions of Concern
    Self-Archiving Policies
    Statement of Informed Consent
    Terms of Use