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2024, Vol: 8, Issue: 5
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Review Article

Online Publishing Date:
20 / 12 / 2023

 


Diagnosis and management of erythroderma; a systematic review

Hani Hamoud Albalawi, Abdulaziz Talal Altemani, Abdulrahman Saleem Alhweiti, Mazen Hamoud Alatawi, Abdulaziz Abdullah Albalawi, Faisal Shiraz Alharthi, Saleh Sulieman Alatawi, Mohammed Aali Alghamdi, Bandar Ahmed Alamrani, Maram Salim Algrani.


Abstract
Erythroderma, a condition characterized by diffuse erythema and scaling covering at least 90 percent of the skin's surface, poses a serious and potentially life-threatening threat. This systematic study aimed to establish diagnosis and management guidelines for erythroderma. Following PRISMA guidelines, a comprehensive review was conducted using PubMed/Medline, Scopus, and Embase databases focusing on English-language articles from 2010 to 2023. From 279 studies, seven articles were included, mainly comprising surveys and analyses of national databases. Erythroderma, as a clinical sign, can manifest as a consequence of various cutaneous and systemic diseases, drug hypersensitivity reactions, and rarely, Sézary syndrome. In pediatric patients, the clinical presentation encompasses a spectrum of acquired and inherited diseases, including infections, inflammatory skin conditions, ichthyoses, and congenital immunodeficiencies. Diagnosing erythroderma proves challenging due to its syndromatic nature, presenting with nonspecific clinical features. Dermatologists must diligently seek cause-oriented clues, employing multiple biopsies to enhance diagnostic accuracy. Initial management should include nutritional expert evaluation, assessment of fluid imbalance, skin barrier maintenance, sedative anti-histamines, and exclusion of secondary bacterial infection. Given its life-threatening potential, erythroderma might necessitate hospitalization. This study provides valuable insights into the complexities of erythroderma diagnosis and highlights essential considerations for effective management.

Key words: Erythroderma, Exfoliative dermatitis, Erythema, Desquamation.


 
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How to Cite this Article
Pubmed Style

Albalawi HH, Altemani AT, Alhweiti AS, Alatawi MH, Albalawi AA, Alharthi FS, Alatawi SS, Alghamdi MA, Alamrani BA, Algrani MS. Diagnosis and management of erythroderma; a systematic review. IJMDC. 2024; 8(1): 387-395. doi:10.24911/IJMDC.51-1700391422

Web Style

Albalawi HH, Altemani AT, Alhweiti AS, Alatawi MH, Albalawi AA, Alharthi FS, Alatawi SS, Alghamdi MA, Alamrani BA, Algrani MS. Diagnosis and management of erythroderma; a systematic review. https://www.ijmdc.com/?mno=177988 [Access: May 13, 2024]. doi:10.24911/IJMDC.51-1700391422

AMA (American Medical Association) Style

Albalawi HH, Altemani AT, Alhweiti AS, Alatawi MH, Albalawi AA, Alharthi FS, Alatawi SS, Alghamdi MA, Alamrani BA, Algrani MS. Diagnosis and management of erythroderma; a systematic review. IJMDC. 2024; 8(1): 387-395. doi:10.24911/IJMDC.51-1700391422


Vancouver/ICMJE Style

Albalawi HH, Altemani AT, Alhweiti AS, Alatawi MH, Albalawi AA, Alharthi FS, Alatawi SS, Alghamdi MA, Alamrani BA, Algrani MS. Diagnosis and management of erythroderma; a systematic review. IJMDC. (2024), [cited May 13, 2024]; 8(1): 387-395. doi:10.24911/IJMDC.51-1700391422


Harvard Style

Albalawi, H. H., Altemani, . A. T., Alhweiti, . A. S., Alatawi, . M. H., Albalawi, . A. A., Alharthi, . F. S., Alatawi, . S. S., Alghamdi, . M. A., Alamrani, . B. A. & Algrani, . M. S. (2024) Diagnosis and management of erythroderma; a systematic review. IJMDC, 8 (1), 387-395. doi:10.24911/IJMDC.51-1700391422


Turabian Style

Albalawi, Hani Hamoud, Abdulaziz Talal Altemani, Abdulrahman Saleem Alhweiti, Mazen Hamoud Alatawi, Abdulaziz Abdullah Albalawi, Faisal Shiraz Alharthi, Saleh Sulieman Alatawi, Mohammed Aali Alghamdi, Bandar Ahmed Alamrani, and Maram Salim Algrani. 2024. Diagnosis and management of erythroderma; a systematic review. International Journal of Medicine in Developing Countries, 8 (1), 387-395. doi:10.24911/IJMDC.51-1700391422


Chicago Style

Albalawi, Hani Hamoud, Abdulaziz Talal Altemani, Abdulrahman Saleem Alhweiti, Mazen Hamoud Alatawi, Abdulaziz Abdullah Albalawi, Faisal Shiraz Alharthi, Saleh Sulieman Alatawi, Mohammed Aali Alghamdi, Bandar Ahmed Alamrani, and Maram Salim Algrani. "Diagnosis and management of erythroderma; a systematic review." International Journal of Medicine in Developing Countries 8 (2024), 387-395. doi:10.24911/IJMDC.51-1700391422


MLA (The Modern Language Association) Style

Albalawi, Hani Hamoud, Abdulaziz Talal Altemani, Abdulrahman Saleem Alhweiti, Mazen Hamoud Alatawi, Abdulaziz Abdullah Albalawi, Faisal Shiraz Alharthi, Saleh Sulieman Alatawi, Mohammed Aali Alghamdi, Bandar Ahmed Alamrani, and Maram Salim Algrani. "Diagnosis and management of erythroderma; a systematic review." International Journal of Medicine in Developing Countries 8.1 (2024), 387-395. Print. doi:10.24911/IJMDC.51-1700391422


APA (American Psychological Association) Style

Albalawi, H. H., Altemani, . A. T., Alhweiti, . A. S., Alatawi, . M. H., Albalawi, . A. A., Alharthi, . F. S., Alatawi, . S. S., Alghamdi, . M. A., Alamrani, . B. A. & Algrani, . M. S. (2024) Diagnosis and management of erythroderma; a systematic review. International Journal of Medicine in Developing Countries, 8 (1), 387-395. doi:10.24911/IJMDC.51-1700391422




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