Prevalence, Risk Factors, and Management of Conn's syndrome; A Systematic Review

Tariq Mohamed Shaqran; Abdallah Ahmed Alsuliman; Hatem Yousef Alzhrani; Ibrahim Mohammad Alkhrizi; Zainab Yusuf Ahmed; Ahmed Maeen Al Ismail; Khalid Muslih Alsahafi; Nadeen Abdullah Boubshait; Shahad Saad Aljoaid; Qasem Abdulrahman Mahzari

doi:10.24911/IJMDC.51-1702013517

2024, Vol: 8, Issue: 5

8 / 5Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

« Previous Article

Review Article

Online Publishing Date:
25 / 12 / 2023

IJMDC. 2024; 8(1): 487-495

doi: 10.24911/IJMDC.51-1702013517

Prevalence, Risk Factors, and Management of Conn's syndrome; A Systematic Review

Tariq Mohamed Shaqran, Abdallah Ahmed Alsuliman, Hatem Yousef Alzhrani, Ibrahim Mohammad Alkhrizi, Zainab Yusuf Ahmed, Ahmed Maeen Al Ismail, Khalid Muslih Alsahafi, Nadeen Abdullah Boubshait, Shahad Saad Aljoaid, Qasem Abdulrahman Mahzari.

Abstract
Conn syndrome, named after J. W. Conn in 1955, denotes a condition marked by hypertension with an aldosterone-producing adenoma. This adenoma triggers heightened aldosterone secretion from the adrenal glands, resulting in suppressed plasma renin, hypertension, and hypokalemia. This systematic study aimed to explore the prevalence, risk factors, and management of Conn's syndrome. PubMed/Medline and Scopus databases were scrutinized for English-language articles from 2010 to 2023, adhering to PRISMA guidelines. Among 142 studies identified, 10 met the criteria for inclusion. Surveys and analyses of national databases were the predominant research methods. Formerly deemed uncommon, Conn's syndrome now accounts for 5–15% of hypertensive patients. The deleterious impact of aldosterone extends beyond hypertension, affecting various organs. Timely intervention, whether pharmacological (aldosterone antagonists) or surgical (adrenalectomy), proves effective in mitigating these effects. Early diagnosis and appropriate testing are imperative. Salt intake reduction is crucial, given its association with aldosterone-mediated damage. However, patients often exceed the recommended 5 grams per day, posing a challenge for lifestyle interventions. Adrenalectomy, in addition to lowering cardiovascular risk, naturally reduces salt intake. Clinical research underscores the role of dietary salt in predicting cardiovascular risk, emphasizing its significance even with adequate treatment.

Key words: Conn syndrome, Cushing syndrome, aldosterone, cortisol, adrenal tumor, primary aldosteronism, hypertension.

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by Tariq Mohamed Shaqran Articles by Abdallah Ahmed Alsuliman Articles by Hatem Yousef Alzhrani Articles by Ibrahim Mohammad Alkhrizi Articles by Zainab Yusuf Ahmed Articles by Ahmed Maeen Al Ismail Articles by Khalid Muslih Alsahafi Articles by Nadeen Abdullah Boubshait Articles by Shahad Saad Aljoaid Articles by Qasem Abdulrahman Mahzari
	on Google
	on Google Scholar

How to Cite this Article

Pubmed Style

Shaqran TM, Alsuliman AA, Alzhrani HY, Alkhrizi IM, Ahmed ZY, Ismail AMA, Alsahafi KM, Boubshait NA, Aljoaid SS, Mahzari QA. Prevalence, Risk Factors, and Management of Conn's syndrome; A Systematic Review. IJMDC. 2024; 8(1): 487-495. doi:10.24911/IJMDC.51-1702013517

Web Style

Shaqran TM, Alsuliman AA, Alzhrani HY, Alkhrizi IM, Ahmed ZY, Ismail AMA, Alsahafi KM, Boubshait NA, Aljoaid SS, Mahzari QA. Prevalence, Risk Factors, and Management of Conn's syndrome; A Systematic Review. https://www.ijmdc.com/?mno=180458 [Access: May 12, 2024]. doi:10.24911/IJMDC.51-1702013517

AMA (American Medical Association) Style

Shaqran TM, Alsuliman AA, Alzhrani HY, Alkhrizi IM, Ahmed ZY, Ismail AMA, Alsahafi KM, Boubshait NA, Aljoaid SS, Mahzari QA. Prevalence, Risk Factors, and Management of Conn's syndrome; A Systematic Review. IJMDC. 2024; 8(1): 487-495. doi:10.24911/IJMDC.51-1702013517

Vancouver/ICMJE Style

Shaqran TM, Alsuliman AA, Alzhrani HY, Alkhrizi IM, Ahmed ZY, Ismail AMA, Alsahafi KM, Boubshait NA, Aljoaid SS, Mahzari QA. Prevalence, Risk Factors, and Management of Conn's syndrome; A Systematic Review. IJMDC. (2024), [cited May 12, 2024]; 8(1): 487-495. doi:10.24911/IJMDC.51-1702013517

Harvard Style

Shaqran, T. M., Alsuliman, . A. A., Alzhrani, . H. Y., Alkhrizi, . I. M., Ahmed, . Z. Y., Ismail, . A. M. A., Alsahafi, . K. M., Boubshait, . N. A., Aljoaid, . S. S. & Mahzari, . Q. A. (2024) Prevalence, Risk Factors, and Management of Conn's syndrome; A Systematic Review. IJMDC, 8 (1), 487-495. doi:10.24911/IJMDC.51-1702013517

Turabian Style

Shaqran, Tariq Mohamed, Abdallah Ahmed Alsuliman, Hatem Yousef Alzhrani, Ibrahim Mohammad Alkhrizi, Zainab Yusuf Ahmed, Ahmed Maeen Al Ismail, Khalid Muslih Alsahafi, Nadeen Abdullah Boubshait, Shahad Saad Aljoaid, and Qasem Abdulrahman Mahzari. 2024. Prevalence, Risk Factors, and Management of Conn's syndrome; A Systematic Review. International Journal of Medicine in Developing Countries, 8 (1), 487-495. doi:10.24911/IJMDC.51-1702013517

Chicago Style

Shaqran, Tariq Mohamed, Abdallah Ahmed Alsuliman, Hatem Yousef Alzhrani, Ibrahim Mohammad Alkhrizi, Zainab Yusuf Ahmed, Ahmed Maeen Al Ismail, Khalid Muslih Alsahafi, Nadeen Abdullah Boubshait, Shahad Saad Aljoaid, and Qasem Abdulrahman Mahzari. "Prevalence, Risk Factors, and Management of Conn's syndrome; A Systematic Review." International Journal of Medicine in Developing Countries 8 (2024), 487-495. doi:10.24911/IJMDC.51-1702013517

MLA (The Modern Language Association) Style

Shaqran, Tariq Mohamed, Abdallah Ahmed Alsuliman, Hatem Yousef Alzhrani, Ibrahim Mohammad Alkhrizi, Zainab Yusuf Ahmed, Ahmed Maeen Al Ismail, Khalid Muslih Alsahafi, Nadeen Abdullah Boubshait, Shahad Saad Aljoaid, and Qasem Abdulrahman Mahzari. "Prevalence, Risk Factors, and Management of Conn's syndrome; A Systematic Review." International Journal of Medicine in Developing Countries 8.1 (2024), 487-495. Print. doi:10.24911/IJMDC.51-1702013517

APA (American Psychological Association) Style

Shaqran, T. M., Alsuliman, . A. A., Alzhrani, . H. Y., Alkhrizi, . I. M., Ahmed, . Z. Y., Ismail, . A. M. A., Alsahafi, . K. M., Boubshait, . N. A., Aljoaid, . S. S. & Mahzari, . Q. A. (2024) Prevalence, Risk Factors, and Management of Conn's syndrome; A Systematic Review. International Journal of Medicine in Developing Countries, 8 (1), 487-495. doi:10.24911/IJMDC.51-1702013517

Most Viewed Articles

Most Accessed Articles

Marginal adaptation of fixed prosthodontics
Shahad Mohammed Halawani, Sahar Amer Al-Harbi
IJMDC. 2017; 1(2): 78-84
» Abstract » doi: 10.24911/IJMDC.1.2.7

Parasites in central nervous system
Amal Ahmed Mohamed, Asmaa Mohamed Mansour
IJMDC. 2017; 1(2): 72-77
» Abstract » doi: 10.24911/IJMDC.1.2.6

Non-diabetic retinopathy: a case report
Hassan F. Alkwikbi, Nabil Mamon Abdelfattah, Haithem Mamon Abdelfattah
IJMDC. 2017; 1(1): 33-37
» Abstract » doi: 10.24911/IJMDC.1.1.6

Vitamin D deficiency among high school female students in Riyadh
Sahar Mohsen Aldhafeeri, Fatemah Ibraheem Alrawaji, Abrar Mubarak Algharbi, Alanoud Abdullah Alhessan, Ayat Sami Qabaja, Ghaleah Abdulaziz Alnassar, Ghaliah Ofayn Alsulami, Mashael Belal Alrubaian, Norah Abdulaziz Alhatim, Salehah Salih Alotaibi, Zahra Ali Alkhamees
IJMDC. 2017; 1(1): 18-23
» Abstract » doi: 10.24911/IJMDC.1.1.4

Prognosis of chronic complications of diabetes mellitus (DM) after multiple events of diabetic ketoacidosis (DKA)
Baraa Faiez Rajab, Anwar Essa Alamrim, Ali Essa Alamri
IJMDC. 2019; 3(5): 474-479
» Abstract » doi: 10.24911/IJMDC.51-1546551993

Most Downloaded

Top Downloaded Articles

Anti-IL-17 markedly inhibited the in vitro granuloma induced by Schistosoma mansoni soluble egg antigen.
Asmaa Ezz, Irene S. Gmail, Fatma Elzahraa H. Salem, Rabab Salama, Soad Nady
IJMDC. 2018; 2(January 2018): 38-46
» Abstract » doi: 10.24911/IJMDC.2.1.7

Antibiotic Resistance Crisis
Nuha Saad Mobarki, Buthaina Abdullah Almerabi, Ahmad Hattan Hattan
IJMDC. 2019; 3(6): 561-564
» Abstract » doi: 10.24911/IJMDC.51-1549060699

The knowledge of mothers about children malnutrition and associated factors
Anas Abdulrahman Aljohani, Mujahid Abdulrahman Aljohani
IJMDC. 2020; 4(1): 7-11
» Abstract » doi: 10.24911/IJMDC.51-1541620358

Knowledge and attitude of caregivers of cerebral palsy children in Riyadh city
Abdulaziz Alruwaished, Baleegh Ali, Lubna Abdullah Alhowaimil , Abaraa adullah Alhowaimil, Najd Abdullah Alhowaimil, Aminah Alessa
IJMDC. 2020; 4(1): 12-17
» Abstract » doi: 10.24911/IJMDC.51-1547833051

Most Cited Articles

Most Cited Articles

Antibiotic Resistance Crisis
Nuha Saad Mobarki, Buthaina Abdullah Almerabi, Ahmad Hattan Hattan
IJMDC. 2019; 3(6): 561-564
» Abstract » doi: 10.24911/IJMDC.51-1549060699
Cited : 34 times [Click to see citing articles]

Prevalence of depression, anxiety and stress among diabetes mellitus patients in Arar, Northern Saudi Arabia
AMohammed Elamin Mukrim, Nujud Muteb D. Alshammari, Wurud Muteb D. Alshammari, Maali Subhi T. Alshammari, Yousef Nasif R. Alshammari, Abdulaziz Sael M. Alshammari, Maisa Hamad F. Alanazi, Abdulelah Abdulrhman F. Alzammam, Muharib Mana M. Alshammari, Slwa Khaled Abu Asyah, Aseel Jamal Alzuhayri, Mushref Saeid Alshammari
IJMDC. 2019; 3(3): 229-233
» Abstract » doi: 10.24911/IJMDC.51-1542576396
Cited : 8 times [Click to see citing articles]

Knowledge, attitude, and practice of breast self-examination toward breast cancer among female students at King Saud University in Riyadh, Saudi Arabia
Abdullah Nasser Alomair, Dania Ghazi Felemban, Mohannad Sami Felemban, Jameel Abdullah Awadain, Ammar Saud Altowairqi, Nawaf Fawzan Alfawzan, Fatimah Mohammed Almazayen, Abdulrahman Jalwi Korkoman, Nawaf Saad Alrusayyis
IJMDC. 2020; 4(2): 429-434
» Abstract » doi: 10.24911/IJMDC.51-1576668182
Cited : 8 times [Click to see citing articles]

Population awareness about rheumatoid arthritis in Jazan region, Saudi Arabia
Ahmad Ali Hazzazi, Mohssen Hassen Ageeli, Ahmed Ali Muyidi, Abdulaziz Mohammad Abulgasim, Abdullah Ahmad Yateemi, Nabil Alhakami
IJMDC. 2020; 4(3): 668-675
» Abstract » doi: 10.24911/IJMDC.51-1576010943
Cited : 4 times [Click to see citing articles]

Prevalence and factors associated with depression among health care workers in National Guard Hospital in Riyadh, KSA
Noor Mohammad AlFahhad
IJMDC. 2018; 2(September 2018): 92-96
» Abstract » doi: 10.24911/IJMDC.51-1526306040
Cited : 4 times [Click to see citing articles]

About International Journal of Medicine in Developing Countries

Contact Information

How to cite this article