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Original Article
Online Published: 28 Dec 2022
 


Contemporary aminophylline use for status asthmaticus in pediatric ICUs: a questionnaire-based study

Ahmed Abdullah Alsaqer, Munirah Abdulrahman Alrobian, Abdulaziz Alolayan, Ali Alqahtani, Hend Bafagih, Abdullah Qasem.


Abstract
Background: Status asthmaticus is severe acute exacerbation asthma that results in respiratory failure due to the failure of conventional treatment. Aminophylline is one of the methylxanthines used to manage status asthmaticus in the pediatric intensive care unit (PICU). However, aminophylline’s role in managing severe asthma among children is still controversial, and PICUs still use it. There is no data on using aminophylline in Saudi Arabia. This study aimed at assessing the use and causes of using aminophylline in the PICU and the perception of pediatricians on using aminophylline in the PICU.
Methods: A cross-sectional study was conducted on pediatric physicians working in PICUs employing pre-validated questionnaire. The Statistical Package for the Social Sciences program was used to analyze the retrieved data.
Results: One hundred seventy-one pediatricians participated in the study; 85.4% reported IV aminophylline for acute asthma exacerbation, and 69% reported using it if the patient did not improve on other medications. About 68.4% and 83% considered IV aminophylline an effective and safe option, respectively. The side effects of IV aminophylline reported were arrhythmia at 75.3% and gastrointestinal tract side effects at 15.1%.
Conclusion: Aminophylline was found highly used in PICUs in Saudi Arabia; this can be attributed to the perception of pediatricians, as it is a safe and effective treatment option.

Key words: Aminophylline, causes, usage, status asthmaticus, pediatrics, PICU.


 
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How to Cite this Article
Pubmed Style

Alsaqer AA, Alrobian MA, Alolayan A, Alqahtani A, Bafagih H, Qasem A. Contemporary aminophylline use for status asthmaticus in pediatric ICUs: a questionnaire-based study. IJMDC. 2023; 7(3): 418-424. doi:10.24911/IJMDC.51-1666777572

Web Style

Alsaqer AA, Alrobian MA, Alolayan A, Alqahtani A, Bafagih H, Qasem A. Contemporary aminophylline use for status asthmaticus in pediatric ICUs: a questionnaire-based study. https://www.ijmdc.com/?mno=124693 [Access: October 14, 2025]. doi:10.24911/IJMDC.51-1666777572

AMA (American Medical Association) Style

Alsaqer AA, Alrobian MA, Alolayan A, Alqahtani A, Bafagih H, Qasem A. Contemporary aminophylline use for status asthmaticus in pediatric ICUs: a questionnaire-based study. IJMDC. 2023; 7(3): 418-424. doi:10.24911/IJMDC.51-1666777572


Vancouver/ICMJE Style

Alsaqer AA, Alrobian MA, Alolayan A, Alqahtani A, Bafagih H, Qasem A. Contemporary aminophylline use for status asthmaticus in pediatric ICUs: a questionnaire-based study. IJMDC. (2023), [cited October 14, 2025]; 7(3): 418-424. doi:10.24911/IJMDC.51-1666777572


Harvard Style

Alsaqer, A. A., Alrobian, . M. A., Alolayan, . A., Alqahtani, . A., Bafagih, . H. & Qasem, . A. (2023) Contemporary aminophylline use for status asthmaticus in pediatric ICUs: a questionnaire-based study. IJMDC, 7 (3), 418-424. doi:10.24911/IJMDC.51-1666777572


Turabian Style

Alsaqer, Ahmed Abdullah, Munirah Abdulrahman Alrobian, Abdulaziz Alolayan, Ali Alqahtani, Hend Bafagih, and Abdullah Qasem. 2023. Contemporary aminophylline use for status asthmaticus in pediatric ICUs: a questionnaire-based study. International Journal of Medicine in Developing Countries, 7 (3), 418-424. doi:10.24911/IJMDC.51-1666777572


Chicago Style

Alsaqer, Ahmed Abdullah, Munirah Abdulrahman Alrobian, Abdulaziz Alolayan, Ali Alqahtani, Hend Bafagih, and Abdullah Qasem. "Contemporary aminophylline use for status asthmaticus in pediatric ICUs: a questionnaire-based study." International Journal of Medicine in Developing Countries 7 (2023), 418-424. doi:10.24911/IJMDC.51-1666777572


MLA (The Modern Language Association) Style

Alsaqer, Ahmed Abdullah, Munirah Abdulrahman Alrobian, Abdulaziz Alolayan, Ali Alqahtani, Hend Bafagih, and Abdullah Qasem. "Contemporary aminophylline use for status asthmaticus in pediatric ICUs: a questionnaire-based study." International Journal of Medicine in Developing Countries 7.3 (2023), 418-424. Print. doi:10.24911/IJMDC.51-1666777572


APA (American Psychological Association) Style

Alsaqer, A. A., Alrobian, . M. A., Alolayan, . A., Alqahtani, . A., Bafagih, . H. & Qasem, . A. (2023) Contemporary aminophylline use for status asthmaticus in pediatric ICUs: a questionnaire-based study. International Journal of Medicine in Developing Countries, 7 (3), 418-424. doi:10.24911/IJMDC.51-1666777572




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