E-ISSN 1658-7820
 

Review Article

Online Publishing Date:
14 / 10 / 2020

 


Role of serotonin reuptake inhibitor (SSRI) therapies as a therapeutic option for irritable bowel syndrome: a brief review

Ibrahim Mahmoud Ajwah, Waad Maher Alqulayti, Maram Salim Algrani, Maryam Talal Altuwayjiri, Sahar Yahya S Alatawi, Yazeed Saeed M Alqahtani, Razan Kamel Albalawi, Hadeel Ahmed Almutairi, Yassmeen Hmoud Alblowi, Alaa Sulaiman Almehmadi, Muflih Abdullah Saed Albalawi, Abdulmajeed Faisal A Albalawi, Waleed Khaled Alshehri, Maram Ali Jarallah, Wejdan Saleem Aljohani, Rama Osama Abu Alez.


Abstract
Psychological factors are considered very important to be associated with the development of irritable bowel syndrome (IBS). Trials were suggesting that antidepressant therapy may be useful for patients for symptomatic relief in IBS patients. This study is aimed to summarize the role of selective serotonin reuptake inhibitor (SSRI) therapies for IBS. PubMed, Google Scholar, and EBSCO databases were used to systematically search for relevant articles. The terms “antidepressant, functional bowel disorders, and irritable bowel syndrome« were used. Among 107 articles, six randomized controlled trials fulfilled the inclusion criteria. In these studies, the efficacy of selective SSRIs was analyzed in IBS. Different interventions were used although, in most studies, their effect on IBS’s global symptom relief as a primary outcome was investigated. In IBS patients, SSRI was proven to be effective in pain-relieving and symptom improvement. Although clinical practice guidelines suggest the use of SSRI, clinicians should also consider patients’ acceptance for it.

Key words: Functional bowel disorders, systematic review, therapies


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Ibrahim Mahmoud Ajwah
Articles by Waad Maher Alqulayti
Articles by Maram Salim Algrani
Articles by Maryam Talal Altuwayjiri
Articles by Sahar Yahya S Alatawi
Articles by Yazeed Saeed M Alqahtani
Articles by Razan Kamel Albalawi
Articles by Hadeel Ahmed Almutairi
Articles by Yassmeen Hmoud Alblowi
Articles by Alaa Sulaiman Almehmadi
Articles by Muflih Abdullah Saed Albalawi
Articles by Abdulmajeed Faisal A Albalawi
Articles by Waleed Khaled Alshehri
Articles by Maram Ali Jarallah
Articles by Wejdan Saleem Aljohani
Articles by Rama Osama Abu Alez
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Ajwah IM, Alqulayti WM, Algrani MS, Altuwayjiri MT, Alatawi SYS, Alqahtani YSM, Albalawi RK, Almutairi HA, Alblowi YH, Almehmadi AS, Albalawi MAS, Albalawi AFA, Alshehri WK, Jarallah MA, Aljohani WS, Alez ROA. Role of serotonin reuptake inhibitor (SSRI) therapies as a therapeutic option for irritable bowel syndrome: a brief review. IJMDC. 2020; 4(11): 1980-1983. doi:10.24911/IJMDC.51-1598469297


Web Style

Ajwah IM, Alqulayti WM, Algrani MS, Altuwayjiri MT, Alatawi SYS, Alqahtani YSM, Albalawi RK, Almutairi HA, Alblowi YH, Almehmadi AS, Albalawi MAS, Albalawi AFA, Alshehri WK, Jarallah MA, Aljohani WS, Alez ROA. Role of serotonin reuptake inhibitor (SSRI) therapies as a therapeutic option for irritable bowel syndrome: a brief review. https://www.ijmdc.com/?mno=129119 [Access: June 04, 2024]. doi:10.24911/IJMDC.51-1598469297


AMA (American Medical Association) Style

Ajwah IM, Alqulayti WM, Algrani MS, Altuwayjiri MT, Alatawi SYS, Alqahtani YSM, Albalawi RK, Almutairi HA, Alblowi YH, Almehmadi AS, Albalawi MAS, Albalawi AFA, Alshehri WK, Jarallah MA, Aljohani WS, Alez ROA. Role of serotonin reuptake inhibitor (SSRI) therapies as a therapeutic option for irritable bowel syndrome: a brief review. IJMDC. 2020; 4(11): 1980-1983. doi:10.24911/IJMDC.51-1598469297



Vancouver/ICMJE Style

Ajwah IM, Alqulayti WM, Algrani MS, Altuwayjiri MT, Alatawi SYS, Alqahtani YSM, Albalawi RK, Almutairi HA, Alblowi YH, Almehmadi AS, Albalawi MAS, Albalawi AFA, Alshehri WK, Jarallah MA, Aljohani WS, Alez ROA. Role of serotonin reuptake inhibitor (SSRI) therapies as a therapeutic option for irritable bowel syndrome: a brief review. IJMDC. (2020), [cited June 04, 2024]; 4(11): 1980-1983. doi:10.24911/IJMDC.51-1598469297



Harvard Style

Ajwah, I. M., Alqulayti, . W. M., Algrani, . M. S., Altuwayjiri, . M. T., Alatawi, . S. Y. S., Alqahtani, . Y. S. M., Albalawi, . R. K., Almutairi, . H. A., Alblowi, . Y. H., Almehmadi, . A. S., Albalawi, . M. A. S., Albalawi, . A. F. A., Alshehri, . W. K., Jarallah, . M. A., Aljohani, . W. S. & Alez, . R. O. A. (2020) Role of serotonin reuptake inhibitor (SSRI) therapies as a therapeutic option for irritable bowel syndrome: a brief review. IJMDC, 4 (11), 1980-1983. doi:10.24911/IJMDC.51-1598469297



Turabian Style

Ajwah, Ibrahim Mahmoud, Waad Maher Alqulayti, Maram Salim Algrani, Maryam Talal Altuwayjiri, Sahar Yahya S Alatawi, Yazeed Saeed M Alqahtani, Razan Kamel Albalawi, Hadeel Ahmed Almutairi, Yassmeen Hmoud Alblowi, Alaa Sulaiman Almehmadi, Muflih Abdullah Saed Albalawi, Abdulmajeed Faisal A Albalawi, Waleed Khaled Alshehri, Maram Ali Jarallah, Wejdan Saleem Aljohani, and Rama Osama Abu Alez. 2020. Role of serotonin reuptake inhibitor (SSRI) therapies as a therapeutic option for irritable bowel syndrome: a brief review. International Journal of Medicine in Developing Countries, 4 (11), 1980-1983. doi:10.24911/IJMDC.51-1598469297



Chicago Style

Ajwah, Ibrahim Mahmoud, Waad Maher Alqulayti, Maram Salim Algrani, Maryam Talal Altuwayjiri, Sahar Yahya S Alatawi, Yazeed Saeed M Alqahtani, Razan Kamel Albalawi, Hadeel Ahmed Almutairi, Yassmeen Hmoud Alblowi, Alaa Sulaiman Almehmadi, Muflih Abdullah Saed Albalawi, Abdulmajeed Faisal A Albalawi, Waleed Khaled Alshehri, Maram Ali Jarallah, Wejdan Saleem Aljohani, and Rama Osama Abu Alez. "Role of serotonin reuptake inhibitor (SSRI) therapies as a therapeutic option for irritable bowel syndrome: a brief review." International Journal of Medicine in Developing Countries 4 (2020), 1980-1983. doi:10.24911/IJMDC.51-1598469297



MLA (The Modern Language Association) Style

Ajwah, Ibrahim Mahmoud, Waad Maher Alqulayti, Maram Salim Algrani, Maryam Talal Altuwayjiri, Sahar Yahya S Alatawi, Yazeed Saeed M Alqahtani, Razan Kamel Albalawi, Hadeel Ahmed Almutairi, Yassmeen Hmoud Alblowi, Alaa Sulaiman Almehmadi, Muflih Abdullah Saed Albalawi, Abdulmajeed Faisal A Albalawi, Waleed Khaled Alshehri, Maram Ali Jarallah, Wejdan Saleem Aljohani, and Rama Osama Abu Alez. "Role of serotonin reuptake inhibitor (SSRI) therapies as a therapeutic option for irritable bowel syndrome: a brief review." International Journal of Medicine in Developing Countries 4.11 (2020), 1980-1983. Print. doi:10.24911/IJMDC.51-1598469297



APA (American Psychological Association) Style

Ajwah, I. M., Alqulayti, . W. M., Algrani, . M. S., Altuwayjiri, . M. T., Alatawi, . S. Y. S., Alqahtani, . Y. S. M., Albalawi, . R. K., Almutairi, . H. A., Alblowi, . Y. H., Almehmadi, . A. S., Albalawi, . M. A. S., Albalawi, . A. F. A., Alshehri, . W. K., Jarallah, . M. A., Aljohani, . W. S. & Alez, . R. O. A. (2020) Role of serotonin reuptake inhibitor (SSRI) therapies as a therapeutic option for irritable bowel syndrome: a brief review. International Journal of Medicine in Developing Countries, 4 (11), 1980-1983. doi:10.24911/IJMDC.51-1598469297





Most Viewed Articles
Most Accessed Articles

  • Marginal adaptation of fixed prosthodontics
    Shahad Mohammed Halawani, Sahar Amer Al-Harbi
    IJMDC. 2017; 1(2): 78-84
    » Abstract » doi: 10.24911/IJMDC.1.2.7

  • Parasites in central nervous system
    Amal Ahmed Mohamed, Asmaa Mohamed Mansour
    IJMDC. 2017; 1(2): 72-77
    » Abstract » doi: 10.24911/IJMDC.1.2.6

  • Non-diabetic retinopathy: a case report
    Hassan F. Alkwikbi, Nabil Mamon Abdelfattah, Haithem Mamon Abdelfattah
    IJMDC. 2017; 1(1): 33-37
    » Abstract » doi: 10.24911/IJMDC.1.1.6

  • Vitamin D deficiency among high school female students in Riyadh
    Sahar Mohsen Aldhafeeri, Fatemah Ibraheem Alrawaji, Abrar Mubarak Algharbi, Alanoud Abdullah Alhessan, Ayat Sami Qabaja, Ghaleah Abdulaziz Alnassar, Ghaliah Ofayn Alsulami, Mashael Belal Alrubaian, Norah Abdulaziz Alhatim, Salehah Salih Alotaibi, Zahra Ali Alkhamees
    IJMDC. 2017; 1(1): 18-23
    » Abstract » doi: 10.24911/IJMDC.1.1.4

  • Prognosis of chronic complications of diabetes mellitus (DM) after multiple events of diabetic ketoacidosis (DKA)
    Baraa Faiez Rajab, Anwar Essa Alamrim, Ali Essa Alamri
    IJMDC. 2019; 3(5): 474-479
    » Abstract » doi: 10.24911/IJMDC.51-1546551993

  • Most Downloaded
    Top Downloaded Articles

  • Anti-IL-17 markedly inhibited the in vitro granuloma induced by Schistosoma mansoni soluble egg antigen.
    Asmaa Ezz, Irene S. Gmail, Fatma Elzahraa H. Salem, Rabab Salama, Soad Nady
    IJMDC. 2018; 2(January 2018): 38-46
    » Abstract » doi: 10.24911/IJMDC.2.1.7

  • Vitamin D deficiency among high school female students in Riyadh
    Sahar Mohsen Aldhafeeri, Fatemah Ibraheem Alrawaji, Abrar Mubarak Algharbi, Alanoud Abdullah Alhessan, Ayat Sami Qabaja, Ghaleah Abdulaziz Alnassar, Ghaliah Ofayn Alsulami, Mashael Belal Alrubaian, Norah Abdulaziz Alhatim, Salehah Salih Alotaibi, Zahra Ali Alkhamees
    IJMDC. 2017; 1(1): 18-23
    » Abstract » doi: 10.24911/IJMDC.1.1.4

  • Antibiotic Resistance Crisis
    Nuha Saad Mobarki, Buthaina Abdullah Almerabi, Ahmad Hattan Hattan
    IJMDC. 2019; 3(6): 561-564
    » Abstract » doi: 10.24911/IJMDC.51-1549060699

  • The knowledge of mothers about children malnutrition and associated factors
    Anas Abdulrahman Aljohani, Mujahid Abdulrahman Aljohani
    IJMDC. 2020; 4(1): 7-11
    » Abstract » doi: 10.24911/IJMDC.51-1541620358

  • Knowledge and attitude of caregivers of cerebral palsy children in Riyadh city
    Abdulaziz Alruwaished, Baleegh Ali, Lubna Abdullah Alhowaimil , Abaraa adullah Alhowaimil, Najd Abdullah Alhowaimil, Aminah Alessa
    IJMDC. 2020; 4(1): 12-17
    » Abstract » doi: 10.24911/IJMDC.51-1547833051

  • Most Cited Articles
    Most Cited Articles

  • Antibiotic Resistance Crisis
    Nuha Saad Mobarki, Buthaina Abdullah Almerabi, Ahmad Hattan Hattan
    IJMDC. 2019; 3(6): 561-564
    » Abstract » doi: 10.24911/IJMDC.51-1549060699
    Cited : 34 times [Click to see citing articles]

  • Prevalence of depression, anxiety and stress among diabetes mellitus patients in Arar, Northern Saudi Arabia
    AMohammed Elamin Mukrim, Nujud Muteb D. Alshammari, Wurud Muteb D. Alshammari, Maali Subhi T. Alshammari, Yousef Nasif R. Alshammari, Abdulaziz Sael M. Alshammari, Maisa Hamad F. Alanazi, Abdulelah Abdulrhman F. Alzammam, Muharib Mana M. Alshammari, Slwa Khaled Abu Asyah, Aseel Jamal Alzuhayri, Mushref Saeid Alshammari
    IJMDC. 2019; 3(3): 229-233
    » Abstract » doi: 10.24911/IJMDC.51-1542576396
    Cited : 8 times [Click to see citing articles]

  • Knowledge, attitude, and practice of breast self-examination toward breast cancer among female students at King Saud University in Riyadh, Saudi Arabia
    Abdullah Nasser Alomair, Dania Ghazi Felemban, Mohannad Sami Felemban, Jameel Abdullah Awadain, Ammar Saud Altowairqi, Nawaf Fawzan Alfawzan, Fatimah Mohammed Almazayen, Abdulrahman Jalwi Korkoman, Nawaf Saad Alrusayyis
    IJMDC. 2020; 4(2): 429-434
    » Abstract » doi: 10.24911/IJMDC.51-1576668182
    Cited : 8 times [Click to see citing articles]

  • Population awareness about rheumatoid arthritis in Jazan region, Saudi Arabia
    Ahmad Ali Hazzazi, Mohssen Hassen Ageeli, Ahmed Ali Muyidi, Abdulaziz Mohammad Abulgasim, Abdullah Ahmad Yateemi, Nabil Alhakami
    IJMDC. 2020; 4(3): 668-675
    » Abstract » doi: 10.24911/IJMDC.51-1576010943
    Cited : 4 times [Click to see citing articles]

  • Prevalence and factors associated with depression among health care workers in National Guard Hospital in Riyadh, KSA
    Noor Mohammad AlFahhad
    IJMDC. 2018; 2(September 2018): 92-96
    » Abstract » doi: 10.24911/IJMDC.51-1526306040
    Cited : 4 times [Click to see citing articles]