Unilateral periorbital swelling as initial rare presentation of pediatric leukemia

Merai Alshehri; Omar Kirat; Ali M. Almaely; Yazeed Alshahrani; Abdulmohsen Nasser H. Alshahrani; Abdulmajeed A. Alkhathami; Hezam Shalan H. Alshahrani

doi:10.24911/IJMDC.51-1675693216

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Case Report
Online Published: 04 Mar 2023

IJMDC. 2023; 7(7): 1054-1057

doi: 10.24911/IJMDC.51-1675693216

Unilateral periorbital swelling as initial rare presentation of pediatric leukemia

Merai Alshehri, Omar Kirat, Ali M. Almaely, Yazeed Alshahrani, Abdulmohsen Nasser H. Alshahrani, Abdulmajeed A. Alkhathami, Hezam Shalan H. Alshahrani.

Abstract
Background: Acute lymphoblastic leukemia (ALL) is considered the most typical type of cancer in children, representing around 26% of childhood cancer.
Case Presentation: A 13-month-old girl was presented to our clinic who developed unilateral periorbital swelling as her initial sole symptom of ALL. In this report, we described this case with a summary of previously reported cases. The patient previously medically free, was presented with left periorbital swelling and inferior globe displacement, progressing over the preceding 3 weeks. At the initial presentation, slit lamp examination revealed a normal anterior segment with characteristic leukemic retinopathic changes in both eyes with no detected hepatosplenomegaly or enlarged lymph nodes. On investigation, a peripheral smear and bone marrow biopsy showed 80% blast cells. A CT scan showed varying degrees of bilateral extraocular/ocular muscle infiltration. ALL was diagnosed, and the patient immediately underwent induction chemotherapy.
Conclusion: This case highlights the importance of understanding and considering rare, aggressive diseases potentially masquerading as simple periorbital edema.

Key words: Periorbital swelling, children, leukemia

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Pubmed Style

Alshehri M, Kirat O, Almaely AM, Alshahrani Y, Alshahrani ANH, Alkhathami AA, Alshahrani HSH. Unilateral periorbital swelling as initial rare presentation of pediatric leukemia. IJMDC. 2023; 7(7): 1054-1057. doi:10.24911/IJMDC.51-1675693216

Web Style

Alshehri M, Kirat O, Almaely AM, Alshahrani Y, Alshahrani ANH, Alkhathami AA, Alshahrani HSH. Unilateral periorbital swelling as initial rare presentation of pediatric leukemia. https://www.ijmdc.com/?mno=143022 [Access: June 23, 2026]. doi:10.24911/IJMDC.51-1675693216

AMA (American Medical Association) Style

Alshehri M, Kirat O, Almaely AM, Alshahrani Y, Alshahrani ANH, Alkhathami AA, Alshahrani HSH. Unilateral periorbital swelling as initial rare presentation of pediatric leukemia. IJMDC. 2023; 7(7): 1054-1057. doi:10.24911/IJMDC.51-1675693216

Vancouver/ICMJE Style

Alshehri M, Kirat O, Almaely AM, Alshahrani Y, Alshahrani ANH, Alkhathami AA, Alshahrani HSH. Unilateral periorbital swelling as initial rare presentation of pediatric leukemia. IJMDC. (2023), [cited June 23, 2026]; 7(7): 1054-1057. doi:10.24911/IJMDC.51-1675693216

Harvard Style

Alshehri, M., Kirat, . O., Almaely, . A. M., Alshahrani, . Y., Alshahrani, . A. N. H., Alkhathami, . A. A. & Alshahrani, . H. S. H. (2023) Unilateral periorbital swelling as initial rare presentation of pediatric leukemia. IJMDC, 7 (7), 1054-1057. doi:10.24911/IJMDC.51-1675693216

Turabian Style

Alshehri, Merai, Omar Kirat, Ali M. Almaely, Yazeed Alshahrani, Abdulmohsen Nasser H. Alshahrani, Abdulmajeed A. Alkhathami, and Hezam Shalan H. Alshahrani. 2023. Unilateral periorbital swelling as initial rare presentation of pediatric leukemia. International Journal of Medicine in Developing Countries, 7 (7), 1054-1057. doi:10.24911/IJMDC.51-1675693216

Chicago Style

Alshehri, Merai, Omar Kirat, Ali M. Almaely, Yazeed Alshahrani, Abdulmohsen Nasser H. Alshahrani, Abdulmajeed A. Alkhathami, and Hezam Shalan H. Alshahrani. "Unilateral periorbital swelling as initial rare presentation of pediatric leukemia." International Journal of Medicine in Developing Countries 7 (2023), 1054-1057. doi:10.24911/IJMDC.51-1675693216

MLA (The Modern Language Association) Style

Alshehri, Merai, Omar Kirat, Ali M. Almaely, Yazeed Alshahrani, Abdulmohsen Nasser H. Alshahrani, Abdulmajeed A. Alkhathami, and Hezam Shalan H. Alshahrani. "Unilateral periorbital swelling as initial rare presentation of pediatric leukemia." International Journal of Medicine in Developing Countries 7.7 (2023), 1054-1057. Print. doi:10.24911/IJMDC.51-1675693216

APA (American Psychological Association) Style

Alshehri, M., Kirat, . O., Almaely, . A. M., Alshahrani, . Y., Alshahrani, . A. N. H., Alkhathami, . A. A. & Alshahrani, . H. S. H. (2023) Unilateral periorbital swelling as initial rare presentation of pediatric leukemia. International Journal of Medicine in Developing Countries, 7 (7), 1054-1057. doi:10.24911/IJMDC.51-1675693216

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