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Review Article
Online Published: 01 Mar 2024
 


The role of low-molecular-weight heparin on recurrent abortion: a review

Taraji Saeed Alrehaili, Mohamed Abdulrahman Alnajjar, Mohammed Saeed Alrehaili, Abdulellah Ismail Alqurashi, Muhammad Essam Aldabbagh.


Abstract
Recurrent abortion (RA) remains a significant challenge in gynecological practice. It is not only emotionally devastating for pregnant women but is also medically challenging. RA is the spontaneous loss in the first trimester of three or more consecutive pregnancies. The current review was aimed at investigating the role of low-molecular-weight heparin (LMWH) in RA. The online databases MEDLINE and Google Scholar were used to perform a literature search for publications published between 2015 and 2013, without any date or language restrictions. We used a combination of relevant search terms “role, low, molecular, weight, heparin, recurrent, and abortion.” We independently identified publications and systematically screened titles, abstracts, and full texts of the collected publications. LMWH was found to be used to treat RA due to its anticoagulants and anti-inflammatory effect. Its use is associated with a substantial improvement in live birth rates in most studies reviewed, with a few inconclusive. There was no significant improvement in late pregnancy complications in women treated with LMWH in the control group. Women treated with LMWH experienced very few adverse medication responses, and those that did occur were often moderate and self-limiting, making LMWH therapy a safe option. To create a consensus recommendation on the treatment of RA, further research on the use of LMWH is required, ideally in the form of sizable multicenter randomized control trials.

Key words: Role, low, molecular, weight, heparin, recurrent, abortion.


 
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How to Cite this Article
Pubmed Style

Alrehaili TS, Alnajjar MA, Alrehaili MS, Alqurashi AI, Aldabbagh ME. The role of low-molecular-weight heparin on recurrent abortion: a review. IJMDC. 2024; 8(4): 1781-1785. doi:10.24911/IJMDC.51-1705268912

Web Style

Alrehaili TS, Alnajjar MA, Alrehaili MS, Alqurashi AI, Aldabbagh ME. The role of low-molecular-weight heparin on recurrent abortion: a review. https://www.ijmdc.com/?mno=185327 [Access: December 06, 2024]. doi:10.24911/IJMDC.51-1705268912

AMA (American Medical Association) Style

Alrehaili TS, Alnajjar MA, Alrehaili MS, Alqurashi AI, Aldabbagh ME. The role of low-molecular-weight heparin on recurrent abortion: a review. IJMDC. 2024; 8(4): 1781-1785. doi:10.24911/IJMDC.51-1705268912


Vancouver/ICMJE Style

Alrehaili TS, Alnajjar MA, Alrehaili MS, Alqurashi AI, Aldabbagh ME. The role of low-molecular-weight heparin on recurrent abortion: a review. IJMDC. (2024), [cited December 06, 2024]; 8(4): 1781-1785. doi:10.24911/IJMDC.51-1705268912


Harvard Style

Alrehaili, T. S., Alnajjar, . M. A., Alrehaili, . M. S., Alqurashi, . A. I. & Aldabbagh, . M. E. (2024) The role of low-molecular-weight heparin on recurrent abortion: a review. IJMDC, 8 (4), 1781-1785. doi:10.24911/IJMDC.51-1705268912


Turabian Style

Alrehaili, Taraji Saeed, Mohamed Abdulrahman Alnajjar, Mohammed Saeed Alrehaili, Abdulellah Ismail Alqurashi, and Muhammad Essam Aldabbagh. 2024. The role of low-molecular-weight heparin on recurrent abortion: a review. International Journal of Medicine in Developing Countries, 8 (4), 1781-1785. doi:10.24911/IJMDC.51-1705268912


Chicago Style

Alrehaili, Taraji Saeed, Mohamed Abdulrahman Alnajjar, Mohammed Saeed Alrehaili, Abdulellah Ismail Alqurashi, and Muhammad Essam Aldabbagh. "The role of low-molecular-weight heparin on recurrent abortion: a review." International Journal of Medicine in Developing Countries 8 (2024), 1781-1785. doi:10.24911/IJMDC.51-1705268912


MLA (The Modern Language Association) Style

Alrehaili, Taraji Saeed, Mohamed Abdulrahman Alnajjar, Mohammed Saeed Alrehaili, Abdulellah Ismail Alqurashi, and Muhammad Essam Aldabbagh. "The role of low-molecular-weight heparin on recurrent abortion: a review." International Journal of Medicine in Developing Countries 8.4 (2024), 1781-1785. Print. doi:10.24911/IJMDC.51-1705268912


APA (American Psychological Association) Style

Alrehaili, T. S., Alnajjar, . M. A., Alrehaili, . M. S., Alqurashi, . A. I. & Aldabbagh, . M. E. (2024) The role of low-molecular-weight heparin on recurrent abortion: a review. International Journal of Medicine in Developing Countries, 8 (4), 1781-1785. doi:10.24911/IJMDC.51-1705268912




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