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Review Article
Online Published: 20 Aug 2025
 


Effectiveness of mindfulness-based interventions on fertility-related stress: A systematic review

Ahlam M.s. Hakami, Arwa H. Alammari, Abdullah S. Alamer, Ali M.h.a. Al-ibrahim, Marwa A. Masmali, Sharifah A. Komeit, Jawaher S. Farji, Wehad A. Mohammed, Remaz R. Ramily, Buthaina T. Bokhader, Faisal A. Kariri.


Abstract
Infertility is a global health concern that significantly impacts psychological well-being, often leading to increased levels of stress, anxiety, and depression. Mindfulness-based interventions (MBIs), such as mindfulness- based stress reduction and mindfulness-based cognitive therapy, have shown promise in alleviating psychological distress across clinical populations. This systematic review aimed to evaluate the effectiveness of MBIs in reducing fertility-related stress and associated psychological outcomes in women undergoing infertility treatment. This review was conducted according to PRISMA guidelines and registered in PROSPERO. A comprehensive literature search was conducted up to March 2024. Studies were eligible if they evaluated MBIs in infertile women and measured outcomes including stress, anxiety, depression, self-efficacy, infertility adjustment, mindfulness awareness, or quality of life. Risk of bias was assessed using the modified Downs and Black checklist. Out of 1,991 records identified, seven studies met the inclusion criteria. Most studies were randomized controlled trials with sample sizes ranging from 34 to 100 participants. MBIs were associated with significant reductions in stress, anxiety, and depressive symptoms. Improvements were also observed in self-efficacy, infertility adjustment, mindfulness awareness, and overall quality of life. Methodological quality ranged from fair to excellent, with four studies scoring ≥24 out of 28. MBIs are effective in reducing psychological distress and enhancing emotional well-being among women facing infertility. These findings support the integration of MBIs into fertility care as a holistic approach to address the emotional needs of patients. Further large-scale studies with standardized protocols and long-term follow-up are recommended.

Key words: mindfulness, infertility, stress, anxiety, quality of life, self-efficacy.


 
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How to Cite this Article
Pubmed Style

Hakami AM, Alammari AH, Alamer AS, Al-ibrahim AM, Masmali MA, Komeit SA, Farji JS, Mohammed WA, Ramily RR, Bokhader BT, Kariri FA. Effectiveness of mindfulness-based interventions on fertility-related stress: A systematic review. IJMDC. 2025; 9(7): 1642-1650. doi:10.24911/IJMDC.51-1749263897

Web Style

Hakami AM, Alammari AH, Alamer AS, Al-ibrahim AM, Masmali MA, Komeit SA, Farji JS, Mohammed WA, Ramily RR, Bokhader BT, Kariri FA. Effectiveness of mindfulness-based interventions on fertility-related stress: A systematic review. https://www.ijmdc.com/?mno=263251 [Access: October 14, 2025]. doi:10.24911/IJMDC.51-1749263897

AMA (American Medical Association) Style

Hakami AM, Alammari AH, Alamer AS, Al-ibrahim AM, Masmali MA, Komeit SA, Farji JS, Mohammed WA, Ramily RR, Bokhader BT, Kariri FA. Effectiveness of mindfulness-based interventions on fertility-related stress: A systematic review. IJMDC. 2025; 9(7): 1642-1650. doi:10.24911/IJMDC.51-1749263897


Vancouver/ICMJE Style

Hakami AM, Alammari AH, Alamer AS, Al-ibrahim AM, Masmali MA, Komeit SA, Farji JS, Mohammed WA, Ramily RR, Bokhader BT, Kariri FA. Effectiveness of mindfulness-based interventions on fertility-related stress: A systematic review. IJMDC. (2025), [cited October 14, 2025]; 9(7): 1642-1650. doi:10.24911/IJMDC.51-1749263897


Harvard Style

Hakami, A. M., Alammari, . A. H., Alamer, . A. S., Al-ibrahim, . A. M., Masmali, . M. A., Komeit, . S. A., Farji, . J. S., Mohammed, . W. A., Ramily, . R. R., Bokhader, . B. T. & Kariri, . F. A. (2025) Effectiveness of mindfulness-based interventions on fertility-related stress: A systematic review. IJMDC, 9 (7), 1642-1650. doi:10.24911/IJMDC.51-1749263897


Turabian Style

Hakami, Ahlam M.s., Arwa H. Alammari, Abdullah S. Alamer, Ali M.h.a. Al-ibrahim, Marwa A. Masmali, Sharifah A. Komeit, Jawaher S. Farji, Wehad A. Mohammed, Remaz R. Ramily, Buthaina T. Bokhader, and Faisal A. Kariri. 2025. Effectiveness of mindfulness-based interventions on fertility-related stress: A systematic review. International Journal of Medicine in Developing Countries, 9 (7), 1642-1650. doi:10.24911/IJMDC.51-1749263897


Chicago Style

Hakami, Ahlam M.s., Arwa H. Alammari, Abdullah S. Alamer, Ali M.h.a. Al-ibrahim, Marwa A. Masmali, Sharifah A. Komeit, Jawaher S. Farji, Wehad A. Mohammed, Remaz R. Ramily, Buthaina T. Bokhader, and Faisal A. Kariri. "Effectiveness of mindfulness-based interventions on fertility-related stress: A systematic review." International Journal of Medicine in Developing Countries 9 (2025), 1642-1650. doi:10.24911/IJMDC.51-1749263897


MLA (The Modern Language Association) Style

Hakami, Ahlam M.s., Arwa H. Alammari, Abdullah S. Alamer, Ali M.h.a. Al-ibrahim, Marwa A. Masmali, Sharifah A. Komeit, Jawaher S. Farji, Wehad A. Mohammed, Remaz R. Ramily, Buthaina T. Bokhader, and Faisal A. Kariri. "Effectiveness of mindfulness-based interventions on fertility-related stress: A systematic review." International Journal of Medicine in Developing Countries 9.7 (2025), 1642-1650. Print. doi:10.24911/IJMDC.51-1749263897


APA (American Psychological Association) Style

Hakami, A. M., Alammari, . A. H., Alamer, . A. S., Al-ibrahim, . A. M., Masmali, . M. A., Komeit, . S. A., Farji, . J. S., Mohammed, . W. A., Ramily, . R. R., Bokhader, . B. T. & Kariri, . F. A. (2025) Effectiveness of mindfulness-based interventions on fertility-related stress: A systematic review. International Journal of Medicine in Developing Countries, 9 (7), 1642-1650. doi:10.24911/IJMDC.51-1749263897




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