Abstract
Background: Adenocarcinoma is a common cancer originating in glandular tissues across different organs. This report presents an unusual case of adenocarcinoma, describing its clinical progression, diagnostic challenges, and treatment plan.
Case Presentation: A 47-year-old woman, who was otherwise healthy, presented with severe, intermittent headache for 1 month, which woke her from sleep and was associated with blurred vision. Upon examination there were bilateral papilledema, with no focal neurological deficits. A right temporoparietal mass with a 7-mm midline shift was observed on CT/MRI. The patient was admitted and underwent a craniotomy for lesion excision, followed by dexamethasone and Keppra. Further imaging revealed a nonspecific pulmonary nodule, suspicious thyroid nodules, and a distal descending/sigmoid colon lesion, with potential lymph node involvement and peritoneal deposits. A colonoscopy confirmed an obstructing colonic mass, resulting in a referral for laparoscopic hemicolectomy.
Conclusion: This case underscores the importance of early diagnosis and a comprehensive treatment approach in the management of adenocarcinoma. This study highlights the value of a multidisciplinary team in addressing complex cases and discusses potential complications and outcomes. Although adenocarcinoma is a well-recognized cancer, its presentation can vary significantly. Early identification and prompt intervention are crucial for better patient outcomes. Further research is needed to refine the treatment strategies for such rare presentations.

Key words: Colon cancer, malignancy, oncology, headache