E-ISSN 1658-7820
 
2025, Vol: 9, Issue: 12
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Case Series
Online Published: 16 Sep 2025
 


The role of bone scan in confirming the diagnosis of foot and ankle complex regional pain syndrome: a case series

Tariq N. Alotaibi, Laila M. Alsabbagh, Layan S. Alsuhaibani, Wessal A. Alhomaied.


Abstract
Background: The pathophysiology of complex regional pain syndrome (CRPS) remains poorly understood and is usually diagnosed clinically. Magnetic resonance imaging (MRI) was initially thought to be the most effective method of diagnosing CRPS, but new studies showed that there is no specific MRI feature that might differentiate CRPS patients from healthy individuals. Studies have shown mixed results of diagnostic reliability.
Case Presentation: In this study, four patients were presented who had a Tc-99m bone scintigraphy scan to confirm the diagnosis of CRPS. The application of this imaging method was demonstrated in clinical settings to reveal that these patients had CRPS. Each case had different difficulties; in three of four cases, a bone scan was able to establish the typical appearance of CRPS. Bone scans facilitated a timely diagnosis and guided subsequent management approaches. A bone scan was not able to confirm the diagnosis in one patient since she had cellulitis.
Conclusion: The findings of this study underscore the significant role of bone scans in confirming the diagnosis of CRPS within the foot and ankle region.

Key words: Bone scan, bone scintigraphy, foot and ankle, complex regional pain syndrome, case series


 
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How to Cite this Article
Pubmed Style

Alotaibi TN, Alsabbagh LM, Alsuhaibani LS, Alhomaied WA. The role of bone scan in confirming the diagnosis of foot and ankle complex regional pain syndrome: a case series. IJMDC. Online First: 16 Sep, 2025. doi:10.24911/IJMDC.51-1754085771

Web Style

Alotaibi TN, Alsabbagh LM, Alsuhaibani LS, Alhomaied WA. The role of bone scan in confirming the diagnosis of foot and ankle complex regional pain syndrome: a case series. https://www.ijmdc.com/?mno=274862 [Access: October 13, 2025]. doi:10.24911/IJMDC.51-1754085771

AMA (American Medical Association) Style

Alotaibi TN, Alsabbagh LM, Alsuhaibani LS, Alhomaied WA. The role of bone scan in confirming the diagnosis of foot and ankle complex regional pain syndrome: a case series. IJMDC. Online First: 16 Sep, 2025. doi:10.24911/IJMDC.51-1754085771


Vancouver/ICMJE Style

Alotaibi TN, Alsabbagh LM, Alsuhaibani LS, Alhomaied WA. The role of bone scan in confirming the diagnosis of foot and ankle complex regional pain syndrome: a case series. IJMDC, [cited October 13, 2025]; Online First: 16 Sep, 2025. doi:10.24911/IJMDC.51-1754085771


Harvard Style

Alotaibi, T. N., Alsabbagh, . L. M., Alsuhaibani, . L. S. & Alhomaied, . W. A. (2025) The role of bone scan in confirming the diagnosis of foot and ankle complex regional pain syndrome: a case series. IJMDC, Online First: 16 Sep, 2025. doi:10.24911/IJMDC.51-1754085771


Turabian Style

Alotaibi, Tariq N., Laila M. Alsabbagh, Layan S. Alsuhaibani, and Wessal A. Alhomaied. 2025. The role of bone scan in confirming the diagnosis of foot and ankle complex regional pain syndrome: a case series. International Journal of Medicine in Developing Countries, Online First: 16 Sep, 2025. doi:10.24911/IJMDC.51-1754085771


Chicago Style

Alotaibi, Tariq N., Laila M. Alsabbagh, Layan S. Alsuhaibani, and Wessal A. Alhomaied. "The role of bone scan in confirming the diagnosis of foot and ankle complex regional pain syndrome: a case series." International Journal of Medicine in Developing Countries Online First: 16 Sep, 2025. doi:10.24911/IJMDC.51-1754085771


MLA (The Modern Language Association) Style

Alotaibi, Tariq N., Laila M. Alsabbagh, Layan S. Alsuhaibani, and Wessal A. Alhomaied. "The role of bone scan in confirming the diagnosis of foot and ankle complex regional pain syndrome: a case series." International Journal of Medicine in Developing Countries Online First: 16 Sep, 2025. Web. 13 Oct 2025 doi:10.24911/IJMDC.51-1754085771


APA (American Psychological Association) Style

Alotaibi, T. N., Alsabbagh, . L. M., Alsuhaibani, . L. S. & Alhomaied, . W. A. (2025) The role of bone scan in confirming the diagnosis of foot and ankle complex regional pain syndrome: a case series. International Journal of Medicine in Developing Countries, Online First: 16 Sep, 2025. doi:10.24911/IJMDC.51-1754085771




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