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2026, Vol: 10, Issue: 6
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Case Report
Online Published: 25 Jun 2026
 


Androgen insensitivity syndrome: a rare case report

Mohammad Othman, Marah Qudaih, Renad Sarhan, Ghazal Qronfla, Rouz Banjar, Lama Ghazi, Remaz Yahya, Raneem Yahya, Reem Qabil.


Abstract
Background:
Hermaphroditism or intersex is a condition in which the individual's genitalia are ambiguous. It is possible for the ovarian and testicular tissues to be separated or to fuse together to form an ovotestis, which is extremely rare in humans.
Case Presentation:
A 38-year-old Saudi woman came to the clinic complaining of primary infertility for the past 19 years. She was married to a 40-year-old male. The wife complained of masses in her labia that are sometimes painful during sex. On examining the labia on both side, a small mobile mass was tender to strong touch toward the lower part of the labia and can be reduced intrabdominally through the inguinal ring. This raised the suspicion of being a hermaphrodite. On karyotyping, the patient was found to have XY chromosomes. Bilateral orchidectomy was conducted. The patient was discharged on the third day, well, and was seen after 6 weeks and 12 weeks in good health.
Conclusion:
Androgen insensitivity syndrome is a rare disease that should be acknowledged by doctors when diagnosing patients with ambiguous genitalia or later in life with infertility. Adult patients with AIS might be challenging to manage, but family support is one of the pillars of management.

Key words: Androgen insensitivity syndrome, infertility, orchidectomy, labial mass, hermaphrodite, karyotype, case report


 
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Pubmed Style

Othman M, Qudaih M, Sarhan R, Qronfla G, Banjar R, Ghazi L, Yahya R, Yahya R, Qabil R. Androgen insensitivity syndrome: a rare case report. IJMDC. Online First: 25 Jun, 2026. doi:10.24911/IJMDC.51-1776590347

Web Style

Othman M, Qudaih M, Sarhan R, Qronfla G, Banjar R, Ghazi L, Yahya R, Yahya R, Qabil R. Androgen insensitivity syndrome: a rare case report. https://www.ijmdc.com/?mno=317925 [Access: June 27, 2026]. doi:10.24911/IJMDC.51-1776590347

AMA (American Medical Association) Style

Othman M, Qudaih M, Sarhan R, Qronfla G, Banjar R, Ghazi L, Yahya R, Yahya R, Qabil R. Androgen insensitivity syndrome: a rare case report. IJMDC. Online First: 25 Jun, 2026. doi:10.24911/IJMDC.51-1776590347


Vancouver/ICMJE Style

Othman M, Qudaih M, Sarhan R, Qronfla G, Banjar R, Ghazi L, Yahya R, Yahya R, Qabil R. Androgen insensitivity syndrome: a rare case report. IJMDC, [cited June 27, 2026]; Online First: 25 Jun, 2026. doi:10.24911/IJMDC.51-1776590347


Harvard Style

Othman, M., Qudaih, . M., Sarhan, . R., Qronfla, . G., Banjar, . R., Ghazi, . L., Yahya, . R., Yahya, . R. & Qabil, . R. (2026) Androgen insensitivity syndrome: a rare case report. IJMDC, Online First: 25 Jun, 2026. doi:10.24911/IJMDC.51-1776590347


Turabian Style

Othman, Mohammad, Marah Qudaih, Renad Sarhan, Ghazal Qronfla, Rouz Banjar, Lama Ghazi, Remaz Yahya, Raneem Yahya, and Reem Qabil. 2026. Androgen insensitivity syndrome: a rare case report. International Journal of Medicine in Developing Countries, Online First: 25 Jun, 2026. doi:10.24911/IJMDC.51-1776590347


Chicago Style

Othman, Mohammad, Marah Qudaih, Renad Sarhan, Ghazal Qronfla, Rouz Banjar, Lama Ghazi, Remaz Yahya, Raneem Yahya, and Reem Qabil. "Androgen insensitivity syndrome: a rare case report." International Journal of Medicine in Developing Countries Online First: 25 Jun, 2026. doi:10.24911/IJMDC.51-1776590347


MLA (The Modern Language Association) Style

Othman, Mohammad, Marah Qudaih, Renad Sarhan, Ghazal Qronfla, Rouz Banjar, Lama Ghazi, Remaz Yahya, Raneem Yahya, and Reem Qabil. "Androgen insensitivity syndrome: a rare case report." International Journal of Medicine in Developing Countries Online First: 25 Jun, 2026. Web. 27 Jun 2026 doi:10.24911/IJMDC.51-1776590347


APA (American Psychological Association) Style

Othman, M., Qudaih, . M., Sarhan, . R., Qronfla, . G., Banjar, . R., Ghazi, . L., Yahya, . R., Yahya, . R. & Qabil, . R. (2026) Androgen insensitivity syndrome: a rare case report. International Journal of Medicine in Developing Countries, Online First: 25 Jun, 2026. doi:10.24911/IJMDC.51-1776590347




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