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2026, Vol: 10, Issue: 9
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Original Article
Online Published: 06 Oct 2026
 


Appropriateness of proton pump inhibitor use among patients at King Faisal Hospital in Makkah, Saudi Arabia: a cross-sectional study

Aseel Omar Banasir, Abdulmajeed Awadh Almutaani, Mohammad Abdulaziz Halawani, Walid Yasser Alkarmo, Baher Moamer Alwaraky, Sharaf Mohammed Alsharif, Khawlah Mohammed Alaklabi, Amar Mohammad Alkhotani, Hassan Abdullah Alsolami, Fahd Mohammed Almalki.


Abstract
Objective:
This study aimed to assess the prevalence of appropriate versus inappropriate proton pump inhibitors (PPIs) use and to identify associated patient-level factors among patients at King Faisal Hospital, Makkah, Saudi Arabia.
Methods:
A cross-sectional study was carried out on patients actively administering PPI using a validated survey. Appropriate PPI use was defined according to correct timing of administration and dosing frequency.
Results:
A total of 320 subjects were enrolled; of these, 70.0% revealed appropriate PPI use. Appropriate use was considerably linked with younger age (p = 0.042), higher education (p = 0.049), shorter illness duration (p = 0.044), and education on correct administration timing (p = 0.001). Higher frequency (67.9%) of those who reported appropriate use also reported well-controlled symptoms compared to those who reported inappropriate use (36.5%). Side effects were uncommon and did not vary between categories (p = 0.304).
Conclusion:
Almost one-third of PPI users displayed inappropriate usage. Education of patients on correct PPI timing was the single most powerful modifiable determinant of appropriate use and symptom control. Consequently, counseling programs are strongly endorsed, particularly for older subjects and those with lower education.

Key words: GERD, medication appropriateness, patient education, proton pump inhibitors, Saudi Arabia.


 
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How to Cite this Article
Pubmed Style

Banasir AO, Almutaani AA, Halawani MA, Alkarmo WY, Alwaraky BM, Alsharif SM, Alaklabi KM, Alkhotani AM, Alsolami HA, Almalki FM. Appropriateness of proton pump inhibitor use among patients at King Faisal Hospital in Makkah, Saudi Arabia: a cross-sectional study. IJMDC. Online First: 06 Oct, 2026. doi:10.24911/IJMDC.51-1786944012

Web Style

Banasir AO, Almutaani AA, Halawani MA, Alkarmo WY, Alwaraky BM, Alsharif SM, Alaklabi KM, Alkhotani AM, Alsolami HA, Almalki FM. Appropriateness of proton pump inhibitor use among patients at King Faisal Hospital in Makkah, Saudi Arabia: a cross-sectional study. https://www.ijmdc.com/?mno=331593 [Access: October 07, 2026]. doi:10.24911/IJMDC.51-1786944012

AMA (American Medical Association) Style

Banasir AO, Almutaani AA, Halawani MA, Alkarmo WY, Alwaraky BM, Alsharif SM, Alaklabi KM, Alkhotani AM, Alsolami HA, Almalki FM. Appropriateness of proton pump inhibitor use among patients at King Faisal Hospital in Makkah, Saudi Arabia: a cross-sectional study. IJMDC. Online First: 06 Oct, 2026. doi:10.24911/IJMDC.51-1786944012


Vancouver/ICMJE Style

Banasir AO, Almutaani AA, Halawani MA, Alkarmo WY, Alwaraky BM, Alsharif SM, Alaklabi KM, Alkhotani AM, Alsolami HA, Almalki FM. Appropriateness of proton pump inhibitor use among patients at King Faisal Hospital in Makkah, Saudi Arabia: a cross-sectional study. IJMDC, [cited October 07, 2026]; Online First: 06 Oct, 2026. doi:10.24911/IJMDC.51-1786944012


Harvard Style

Banasir, A. O., Almutaani, . A. A., Halawani, . M. A., Alkarmo, . W. Y., Alwaraky, . B. M., Alsharif, . S. M., Alaklabi, . K. M., Alkhotani, . A. M., Alsolami, . H. A. & Almalki, . F. M. (2026) Appropriateness of proton pump inhibitor use among patients at King Faisal Hospital in Makkah, Saudi Arabia: a cross-sectional study. IJMDC, Online First: 06 Oct, 2026. doi:10.24911/IJMDC.51-1786944012


Turabian Style

Banasir, Aseel Omar, Abdulmajeed Awadh Almutaani, Mohammad Abdulaziz Halawani, Walid Yasser Alkarmo, Baher Moamer Alwaraky, Sharaf Mohammed Alsharif, Khawlah Mohammed Alaklabi, Amar Mohammad Alkhotani, Hassan Abdullah Alsolami, and Fahd Mohammed Almalki. 2026. Appropriateness of proton pump inhibitor use among patients at King Faisal Hospital in Makkah, Saudi Arabia: a cross-sectional study. International Journal of Medicine in Developing Countries, Online First: 06 Oct, 2026. doi:10.24911/IJMDC.51-1786944012


Chicago Style

Banasir, Aseel Omar, Abdulmajeed Awadh Almutaani, Mohammad Abdulaziz Halawani, Walid Yasser Alkarmo, Baher Moamer Alwaraky, Sharaf Mohammed Alsharif, Khawlah Mohammed Alaklabi, Amar Mohammad Alkhotani, Hassan Abdullah Alsolami, and Fahd Mohammed Almalki. "Appropriateness of proton pump inhibitor use among patients at King Faisal Hospital in Makkah, Saudi Arabia: a cross-sectional study." International Journal of Medicine in Developing Countries Online First: 06 Oct, 2026. doi:10.24911/IJMDC.51-1786944012


MLA (The Modern Language Association) Style

Banasir, Aseel Omar, Abdulmajeed Awadh Almutaani, Mohammad Abdulaziz Halawani, Walid Yasser Alkarmo, Baher Moamer Alwaraky, Sharaf Mohammed Alsharif, Khawlah Mohammed Alaklabi, Amar Mohammad Alkhotani, Hassan Abdullah Alsolami, and Fahd Mohammed Almalki. "Appropriateness of proton pump inhibitor use among patients at King Faisal Hospital in Makkah, Saudi Arabia: a cross-sectional study." International Journal of Medicine in Developing Countries Online First: 06 Oct, 2026. Web. 07 Oct 2026 doi:10.24911/IJMDC.51-1786944012


APA (American Psychological Association) Style

Banasir, A. O., Almutaani, . A. A., Halawani, . M. A., Alkarmo, . W. Y., Alwaraky, . B. M., Alsharif, . S. M., Alaklabi, . K. M., Alkhotani, . A. M., Alsolami, . H. A. & Almalki, . F. M. (2026) Appropriateness of proton pump inhibitor use among patients at King Faisal Hospital in Makkah, Saudi Arabia: a cross-sectional study. International Journal of Medicine in Developing Countries, Online First: 06 Oct, 2026. doi:10.24911/IJMDC.51-1786944012




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