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Original Article
Online Published: 02 Jan 2019
 


Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia

Dalya Alqarni, Asma Alshehri, Raghad Aldehasi, Lujain Al-sayegh, Dania Binrahma, Naeem Alshoaibi.


Abstract
Background: Metformin is a common drug used for antihyperglycemic therapy in type 2 diabetes. Additionally, intravenous (IV) contrast may be administered when using the various imaging techniques to enhance the visualization of body structures, and deterioration of renal function and lactic acidosis - contrast-induced nephropathy (CIN) - may occasionally happen. The purpose of this research was to assess the current guideline of withholding metformin therapy in patients undergoing contrast-enhanced procedures in both the emergency and inpatient settings.
Methodology: A retrospective study was conducted for all patients who were on metformin and underwent a contrast-enhanced imaging procedure (requiring IV contrast) between January and June 2016 at King Abdulaziz University Hospital in Jeddah, Saudi Arabia.
Results: This study involved 107 patients on metformin who received a contrast-enhanced imaging procedure. Out of 107 patients, 26 were admitted through the ER. Independent t-tests were performed to compare GFR and creatinine, before and after the procedure in both, ER and ward patients; they all had non-significant associations.
Conclusion:
In this study none of the ER patients stopped their metformin before they were administered IV contrast.

Key words: Metformin, Creatinine, GFR, Contrast, Emergency


 
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How to Cite this Article
Pubmed Style

Alqarni D, Alshehri A, Aldehasi R, Al-sayegh L, Binrahma D, Alshoaibi N. Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. IJMDC. 2019; 3(1): 26-29. doi:10.24911/IJMDC.51-1543999258

Web Style

Alqarni D, Alshehri A, Aldehasi R, Al-sayegh L, Binrahma D, Alshoaibi N. Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. https://www.ijmdc.com/?mno=20293 [Access: July 03, 2025]. doi:10.24911/IJMDC.51-1543999258

AMA (American Medical Association) Style

Alqarni D, Alshehri A, Aldehasi R, Al-sayegh L, Binrahma D, Alshoaibi N. Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. IJMDC. 2019; 3(1): 26-29. doi:10.24911/IJMDC.51-1543999258


Vancouver/ICMJE Style

Alqarni D, Alshehri A, Aldehasi R, Al-sayegh L, Binrahma D, Alshoaibi N. Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. IJMDC. (2019), [cited July 03, 2025]; 3(1): 26-29. doi:10.24911/IJMDC.51-1543999258


Harvard Style

Alqarni, D., Alshehri, . A., Aldehasi, . R., Al-sayegh, . L., Binrahma, . D. & Alshoaibi, . N. (2019) Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. IJMDC, 3 (1), 26-29. doi:10.24911/IJMDC.51-1543999258


Turabian Style

Alqarni, Dalya, Asma Alshehri, Raghad Aldehasi, Lujain Al-sayegh, Dania Binrahma, and Naeem Alshoaibi. 2019. Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. International Journal of Medicine in Developing Countries, 3 (1), 26-29. doi:10.24911/IJMDC.51-1543999258


Chicago Style

Alqarni, Dalya, Asma Alshehri, Raghad Aldehasi, Lujain Al-sayegh, Dania Binrahma, and Naeem Alshoaibi. "Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia." International Journal of Medicine in Developing Countries 3 (2019), 26-29. doi:10.24911/IJMDC.51-1543999258


MLA (The Modern Language Association) Style

Alqarni, Dalya, Asma Alshehri, Raghad Aldehasi, Lujain Al-sayegh, Dania Binrahma, and Naeem Alshoaibi. "Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia." International Journal of Medicine in Developing Countries 3.1 (2019), 26-29. Print. doi:10.24911/IJMDC.51-1543999258


APA (American Psychological Association) Style

Alqarni, D., Alshehri, . A., Aldehasi, . R., Al-sayegh, . L., Binrahma, . D. & Alshoaibi, . N. (2019) Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. International Journal of Medicine in Developing Countries, 3 (1), 26-29. doi:10.24911/IJMDC.51-1543999258




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