Pain relief in the emergency department using intravenous lidocaine versus nonsteroidal anti-inflammatory drugs and opioids

Mazi Mohammed Alanazi; Nourah A. Bin Klaib; Hana T. Alqahtani; Hatun Mohammed Alnami; Ahmed M. A. Thabet; Danah M. Aljehani; Raghad Ahmad Alsukhayri; Masooma H. Alkhayer; Fatema A. Zabeel; Zainab Ali Abdulhusain

doi:10.24911/IJMDC.51-1733550631

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Review Article
Online Published: 01 Jan 2025

IJMDC. 2024; 8(11): 3364-3369

doi: 10.24911/IJMDC.51-1733550631

Pain relief in the emergency department using intravenous lidocaine versus nonsteroidal anti-inflammatory drugs and opioids

Mazi Mohammed Alanazi, Nourah A. Bin Klaib, Hana T. Alqahtani, Hatun Mohammed Alnami, Ahmed M. A. Thabet, Danah M. Aljehani, Raghad Ahmad Alsukhayri, Masooma H. Alkhayer, Fatema A. Zabeel, Zainab Ali Abdulhusain.

Abstract
To manage pain in the emergency room, this review sought to evaluate the effectiveness of intravenous lidocaine with conventional analgesics. The PubMed, Embase, and ScienceDirect electronic databases were searched between the years 2019 and 2024, and randomized controlled studies that contrasted IV lidocaine with a control group of conventional analgesics were included. It was found that in the treatment of biliary colic, intravenous lidocaine can be a helpful option since it can lessen pain faster than morphine sulfate without causing serious side effects. When given intravenously to emergency department patients with suspected renal colic, the combination of lidocaine and ketorolac produces greater analgesia than lidocaine alone, but it offers no analgesic benefits over ketorolac alone. For both general abdominal discomfort and a subgroup of patients with nephrolithiasis, intravenous hydromorphone was better than intravenous lidocaine.

Key words: Emergency Department, pain relief, intravenous lidocaine, opioids, systemic review

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Pubmed Style

Alanazi MM, Klaib NAB, Alqahtani HT, Alnami HM, Thabet AMA, Aljehani DM, Alsukhayri RA, Alkhayer MH, Zabeel FA, Abdulhusain ZA. Pain relief in the emergency department using intravenous lidocaine versus nonsteroidal anti-inflammatory drugs and opioids. IJMDC. 2024; 8(11): 3364-3369. doi:10.24911/IJMDC.51-1733550631

Web Style

Alanazi MM, Klaib NAB, Alqahtani HT, Alnami HM, Thabet AMA, Aljehani DM, Alsukhayri RA, Alkhayer MH, Zabeel FA, Abdulhusain ZA. Pain relief in the emergency department using intravenous lidocaine versus nonsteroidal anti-inflammatory drugs and opioids. https://www.ijmdc.com/?mno=231959 [Access: October 12, 2025]. doi:10.24911/IJMDC.51-1733550631

AMA (American Medical Association) Style

Alanazi MM, Klaib NAB, Alqahtani HT, Alnami HM, Thabet AMA, Aljehani DM, Alsukhayri RA, Alkhayer MH, Zabeel FA, Abdulhusain ZA. Pain relief in the emergency department using intravenous lidocaine versus nonsteroidal anti-inflammatory drugs and opioids. IJMDC. 2024; 8(11): 3364-3369. doi:10.24911/IJMDC.51-1733550631

Vancouver/ICMJE Style

Alanazi MM, Klaib NAB, Alqahtani HT, Alnami HM, Thabet AMA, Aljehani DM, Alsukhayri RA, Alkhayer MH, Zabeel FA, Abdulhusain ZA. Pain relief in the emergency department using intravenous lidocaine versus nonsteroidal anti-inflammatory drugs and opioids. IJMDC. (2024), [cited October 12, 2025]; 8(11): 3364-3369. doi:10.24911/IJMDC.51-1733550631

Harvard Style

Alanazi, M. M., Klaib, . N. A. B., Alqahtani, . H. T., Alnami, . H. M., Thabet, . A. M. A., Aljehani, . D. M., Alsukhayri, . R. A., Alkhayer, . M. H., Zabeel, . F. A. & Abdulhusain, . Z. A. (2024) Pain relief in the emergency department using intravenous lidocaine versus nonsteroidal anti-inflammatory drugs and opioids. IJMDC, 8 (11), 3364-3369. doi:10.24911/IJMDC.51-1733550631

Turabian Style

Alanazi, Mazi Mohammed, Nourah A. Bin Klaib, Hana T. Alqahtani, Hatun Mohammed Alnami, Ahmed M. A. Thabet, Danah M. Aljehani, Raghad Ahmad Alsukhayri, Masooma H. Alkhayer, Fatema A. Zabeel, and Zainab Ali Abdulhusain. 2024. Pain relief in the emergency department using intravenous lidocaine versus nonsteroidal anti-inflammatory drugs and opioids. International Journal of Medicine in Developing Countries, 8 (11), 3364-3369. doi:10.24911/IJMDC.51-1733550631

Chicago Style

Alanazi, Mazi Mohammed, Nourah A. Bin Klaib, Hana T. Alqahtani, Hatun Mohammed Alnami, Ahmed M. A. Thabet, Danah M. Aljehani, Raghad Ahmad Alsukhayri, Masooma H. Alkhayer, Fatema A. Zabeel, and Zainab Ali Abdulhusain. "Pain relief in the emergency department using intravenous lidocaine versus nonsteroidal anti-inflammatory drugs and opioids." International Journal of Medicine in Developing Countries 8 (2024), 3364-3369. doi:10.24911/IJMDC.51-1733550631

MLA (The Modern Language Association) Style

Alanazi, Mazi Mohammed, Nourah A. Bin Klaib, Hana T. Alqahtani, Hatun Mohammed Alnami, Ahmed M. A. Thabet, Danah M. Aljehani, Raghad Ahmad Alsukhayri, Masooma H. Alkhayer, Fatema A. Zabeel, and Zainab Ali Abdulhusain. "Pain relief in the emergency department using intravenous lidocaine versus nonsteroidal anti-inflammatory drugs and opioids." International Journal of Medicine in Developing Countries 8.11 (2024), 3364-3369. Print. doi:10.24911/IJMDC.51-1733550631

APA (American Psychological Association) Style

Alanazi, M. M., Klaib, . N. A. B., Alqahtani, . H. T., Alnami, . H. M., Thabet, . A. M. A., Aljehani, . D. M., Alsukhayri, . R. A., Alkhayer, . M. H., Zabeel, . F. A. & Abdulhusain, . Z. A. (2024) Pain relief in the emergency department using intravenous lidocaine versus nonsteroidal anti-inflammatory drugs and opioids. International Journal of Medicine in Developing Countries, 8 (11), 3364-3369. doi:10.24911/IJMDC.51-1733550631

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