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2026, Vol: 10, Issue: 3
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Case Report
Online Published: 22 Jan 2026
 


Tadalafil-associated central serous chorioretinopathy: a case report and review of the literature

Abdulelah T. Binyamin, Abdulaziz S. Alrashid, Waleed Talib Batais, Jumanah Mohammed Tirksstani, Abdullah S. Alqahtani.


Abstract
Background:
Central serous chorioretinopathy (CSCR) has been associated with multiple risk factors, and increasing evidence suggested a possible link between phosphodiesterase-5 (PDE5) inhibitors and the development of CSCR. Hence, awareness is important for timely diagnosis and management.
Case Presentation:
A 47-year-old male with a history of well-controlled diabetes mellitus, dyslipidemia, and Parkinson’s disease presented with a 3-day history of blurred vision in the left eye following a single 20 mg dose of tadalafil. Ophthalmic examination revealed reduced visual acuity in the affected eye. Optical coherence tomography demonstrated subretinal fluid with a small pigment epithelial detachment, supporting the diagnosis of central serous chorioretinopathy. The diagnosis was made based on the clinical presentation, recent PDE5 inhibitor use, and imaging findings. The patient was advised to discontinue tadalafil, and close follow-up was arranged. Subsequent evaluation demonstrated improvement in visual symptoms, with signs of subretinal fluid resolution on follow-up imaging, supporting the presumed association between tadalafil use and CSCR.
Conclusion:
This case emphasized on the importance of considering recent PDE5 inhibitor use in patients presenting with acute visual symptoms. Discontinuation of the suspected agent might lead to clinical improvement, and early recognition with prompt intervention might help prevent potential long-term visual complications in drug-associated CSCR.

Key words: Case report, central serous chorioretinopathy, CSCR, tadalafil, case report


 
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Pubmed Style

Binyamin AT, Alrashid AS, Batais WT, Tirksstani JM, Alqahtani AS. Tadalafil-associated central serous chorioretinopathy: a case report and review of the literature. IJMDC. 2026; 10(3): 1063-1066. doi:10.24911/IJMDC.51-1767638587

Web Style

Binyamin AT, Alrashid AS, Batais WT, Tirksstani JM, Alqahtani AS. Tadalafil-associated central serous chorioretinopathy: a case report and review of the literature. https://www.ijmdc.com/?mno=305730 [Access: February 23, 2026]. doi:10.24911/IJMDC.51-1767638587

AMA (American Medical Association) Style

Binyamin AT, Alrashid AS, Batais WT, Tirksstani JM, Alqahtani AS. Tadalafil-associated central serous chorioretinopathy: a case report and review of the literature. IJMDC. 2026; 10(3): 1063-1066. doi:10.24911/IJMDC.51-1767638587


Vancouver/ICMJE Style

Binyamin AT, Alrashid AS, Batais WT, Tirksstani JM, Alqahtani AS. Tadalafil-associated central serous chorioretinopathy: a case report and review of the literature. IJMDC. (2026), [cited February 23, 2026]; 10(3): 1063-1066. doi:10.24911/IJMDC.51-1767638587


Harvard Style

Binyamin, A. T., Alrashid, . A. S., Batais, . W. T., Tirksstani, . J. M. & Alqahtani, . A. S. (2026) Tadalafil-associated central serous chorioretinopathy: a case report and review of the literature. IJMDC, 10 (3), 1063-1066. doi:10.24911/IJMDC.51-1767638587


Turabian Style

Binyamin, Abdulelah T., Abdulaziz S. Alrashid, Waleed Talib Batais, Jumanah Mohammed Tirksstani, and Abdullah S. Alqahtani. 2026. Tadalafil-associated central serous chorioretinopathy: a case report and review of the literature. International Journal of Medicine in Developing Countries, 10 (3), 1063-1066. doi:10.24911/IJMDC.51-1767638587


Chicago Style

Binyamin, Abdulelah T., Abdulaziz S. Alrashid, Waleed Talib Batais, Jumanah Mohammed Tirksstani, and Abdullah S. Alqahtani. "Tadalafil-associated central serous chorioretinopathy: a case report and review of the literature." International Journal of Medicine in Developing Countries 10 (2026), 1063-1066. doi:10.24911/IJMDC.51-1767638587


MLA (The Modern Language Association) Style

Binyamin, Abdulelah T., Abdulaziz S. Alrashid, Waleed Talib Batais, Jumanah Mohammed Tirksstani, and Abdullah S. Alqahtani. "Tadalafil-associated central serous chorioretinopathy: a case report and review of the literature." International Journal of Medicine in Developing Countries 10.3 (2026), 1063-1066. Print. doi:10.24911/IJMDC.51-1767638587


APA (American Psychological Association) Style

Binyamin, A. T., Alrashid, . A. S., Batais, . W. T., Tirksstani, . J. M. & Alqahtani, . A. S. (2026) Tadalafil-associated central serous chorioretinopathy: a case report and review of the literature. International Journal of Medicine in Developing Countries, 10 (3), 1063-1066. doi:10.24911/IJMDC.51-1767638587




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